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Medical proton dosimetry using radioluminescence from aluminium oxide crystals attached to optical-fiber cables

Andersen, C. E.; Edmund, J. M.; Medin, Joakim LU ; Grusell, E.; Jain, M. and Mattsson, Sören LU (2007) In Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment 580(1). p.466-468
Abstract
The prime objective of this study is to investigate if radioluminescence (RL) from carbon-doped aluminum oxide (Al2O3:C) crystals potentially can be used for absorbed dose-rate measurements during proton radiotherapy. The RL from two separate (2 mg) Al2O3:C crystals attached to optical-fiber cables were recorded during irradiations in water in a 175 MeV clinical proton beam. The RL response for low-LET protons in the plateau region of the Bragg curve was found to closely resemble that observed for a clinical 6 MV X-ray beam. An identical response was found in the Bragg peak (where the dose-averaged LET is about 4 keV/mu m) for absorbed doses less than 0.3 Gy. For doses in the range of 0.3-3Gy, we observed a significant decrease in... (More)
The prime objective of this study is to investigate if radioluminescence (RL) from carbon-doped aluminum oxide (Al2O3:C) crystals potentially can be used for absorbed dose-rate measurements during proton radiotherapy. The RL from two separate (2 mg) Al2O3:C crystals attached to optical-fiber cables were recorded during irradiations in water in a 175 MeV clinical proton beam. The RL response for low-LET protons in the plateau region of the Bragg curve was found to closely resemble that observed for a clinical 6 MV X-ray beam. An identical response was found in the Bragg peak (where the dose-averaged LET is about 4 keV/mu m) for absorbed doses less than 0.3 Gy. For doses in the range of 0.3-3Gy, we observed a significant decrease in luminescence efficiency with LET. At 3 Gy, the luminescence efficiency was about 60% in the Bragg-peak region. The study implies that the RL-signal from Al2O3:C could potentially be suitable for medical proton dosimetry in the 0-0.3 Gy range even without any LET-dependent correction factors. (C) 2007 Elsevier B.V. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
radiation-induced luminescence, dosimetry, neutron and proton
in
Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment
volume
580
issue
1
pages
466 - 468
publisher
Elsevier
external identifiers
  • wos:000249741300120
  • scopus:34548247814
ISSN
0167-5087
DOI
10.1016/j.nima.2007.05.129
language
English
LU publication?
yes
id
aaf97f75-c706-4180-915a-ad8a6abd6f0b (old id 655931)
date added to LUP
2007-12-05 10:11:41
date last changed
2017-01-01 06:37:35
@article{aaf97f75-c706-4180-915a-ad8a6abd6f0b,
  abstract     = {The prime objective of this study is to investigate if radioluminescence (RL) from carbon-doped aluminum oxide (Al2O3:C) crystals potentially can be used for absorbed dose-rate measurements during proton radiotherapy. The RL from two separate (2 mg) Al2O3:C crystals attached to optical-fiber cables were recorded during irradiations in water in a 175 MeV clinical proton beam. The RL response for low-LET protons in the plateau region of the Bragg curve was found to closely resemble that observed for a clinical 6 MV X-ray beam. An identical response was found in the Bragg peak (where the dose-averaged LET is about 4 keV/mu m) for absorbed doses less than 0.3 Gy. For doses in the range of 0.3-3Gy, we observed a significant decrease in luminescence efficiency with LET. At 3 Gy, the luminescence efficiency was about 60% in the Bragg-peak region. The study implies that the RL-signal from Al2O3:C could potentially be suitable for medical proton dosimetry in the 0-0.3 Gy range even without any LET-dependent correction factors. (C) 2007 Elsevier B.V. All rights reserved.},
  author       = {Andersen, C. E. and Edmund, J. M. and Medin, Joakim and Grusell, E. and Jain, M. and Mattsson, Sören},
  issn         = {0167-5087},
  keyword      = {radiation-induced luminescence,dosimetry,neutron and proton},
  language     = {eng},
  number       = {1},
  pages        = {466--468},
  publisher    = {Elsevier},
  series       = {Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment},
  title        = {Medical proton dosimetry using radioluminescence from aluminium oxide crystals attached to optical-fiber cables},
  url          = {http://dx.doi.org/10.1016/j.nima.2007.05.129},
  volume       = {580},
  year         = {2007},
}