Absorption-spectroscopy In Tissue-simulating Materials - A Theoretical and Experimental-study of Photon Paths
(1995) In Applied Optics 34(1). p.22-30- Abstract
- A diffusion model of noninvasive absorption spectroscopy was used to determine how the change in signal resulting from a point absorber depends on the position of that absorber relative to the source and detector. This is equivalent to calculating the relative probability that a photon will visit a certain location in tissue before its detection. Experimental mapping of the point-target response in tissue-simulating materials confirmed the accuracy of the model. For steady-state spectroscopy a simple relation was derived between the mean depth visited by detected photons, the source-detector separation, and the optical penetration depth. It was also demonstrated theoretically that combining a pulsed source with time-gated detection... (More)
- A diffusion model of noninvasive absorption spectroscopy was used to determine how the change in signal resulting from a point absorber depends on the position of that absorber relative to the source and detector. This is equivalent to calculating the relative probability that a photon will visit a certain location in tissue before its detection. Experimental mapping of the point-target response in tissue-simulating materials confirmed the accuracy of the model. For steady-state spectroscopy a simple relation was derived between the mean depth visited by detected photons, the source-detector separation, and the optical penetration depth. It was also demonstrated theoretically that combining a pulsed source with time-gated detection provides additional control over the spatial distribution of the photon-visit probability. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2259122
- author
- Patterson, M. S ; Andersson-Engels, Stefan LU ; Wilson, B. C and Osei, E. K
- organization
- publishing date
- 1995
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied Optics
- volume
- 34
- issue
- 1
- pages
- 22 - 30
- publisher
- Optical Society of America
- external identifiers
-
- scopus:0029185321
- ISSN
- 2155-3165
- DOI
- 10.1364/AO.34.000022
- language
- English
- LU publication?
- yes
- id
- 670d0b38-afb0-4ff7-b04e-2bb38aaf655f (old id 2259122)
- date added to LUP
- 2016-04-04 08:30:25
- date last changed
- 2021-06-13 05:59:37
@article{670d0b38-afb0-4ff7-b04e-2bb38aaf655f,
abstract = {{A diffusion model of noninvasive absorption spectroscopy was used to determine how the change in signal resulting from a point absorber depends on the position of that absorber relative to the source and detector. This is equivalent to calculating the relative probability that a photon will visit a certain location in tissue before its detection. Experimental mapping of the point-target response in tissue-simulating materials confirmed the accuracy of the model. For steady-state spectroscopy a simple relation was derived between the mean depth visited by detected photons, the source-detector separation, and the optical penetration depth. It was also demonstrated theoretically that combining a pulsed source with time-gated detection provides additional control over the spatial distribution of the photon-visit probability.}},
author = {{Patterson, M. S and Andersson-Engels, Stefan and Wilson, B. C and Osei, E. K}},
issn = {{2155-3165}},
language = {{eng}},
number = {{1}},
pages = {{22--30}},
publisher = {{Optical Society of America}},
series = {{Applied Optics}},
title = {{Absorption-spectroscopy In Tissue-simulating Materials - A Theoretical and Experimental-study of Photon Paths}},
url = {{https://lup.lub.lu.se/search/files/5181592/2365338.pdf}},
doi = {{10.1364/AO.34.000022}},
volume = {{34}},
year = {{1995}},
}