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Containerless reaction monitoring in ionic liquids by means of Raman microspectroscopy

Lopez-Pastor, Mercedes; Dominguez-Vidal, Ana; Ayora-Canada, Maria Jose; Laurell, Thomas LU ; Valcarcel, Miguel and Lendl, Bernhard (2007) In Lab on A Chip 7(1). p.126-132
Abstract
Reaction monitoring by Raman microspectroscopy in levitated room temperature ionic liquid (RTIL) droplets is reported. Due to their non-volatility, RTIL droplets are well-suited to act as wall-less microreactors. The droplets were produced by a piezoelectric flow-through microdispenser connected to an automated flow injection system and were levitated by an acoustic trap. Taking advantage of the flow system versatility, the sequence of reagents was easily changed to study a model organic reaction: the Knoevenagel condensation. The reaction was followed by Raman microspectrometry and the obtained spectra were analysed using multivariate curve resolution to retrieve the concentration profiles and pure spectra of reactants, intermediates and... (More)
Reaction monitoring by Raman microspectroscopy in levitated room temperature ionic liquid (RTIL) droplets is reported. Due to their non-volatility, RTIL droplets are well-suited to act as wall-less microreactors. The droplets were produced by a piezoelectric flow-through microdispenser connected to an automated flow injection system and were levitated by an acoustic trap. Taking advantage of the flow system versatility, the sequence of reagents was easily changed to study a model organic reaction: the Knoevenagel condensation. The reaction was followed by Raman microspectrometry and the obtained spectra were analysed using multivariate curve resolution to retrieve the concentration profiles and pure spectra of reactants, intermediates and products involved in the reaction. In addition, information about solvation interactions was obtained by monitoring the desolvation process taking place when a volatile co-solvent evaporated from the droplet. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Lab on A Chip
volume
7
issue
1
pages
126 - 132
publisher
Royal Society of Chemistry
external identifiers
  • wos:000244616200019
  • scopus:33845762012
ISSN
1473-0189
DOI
10.1039/b608618g
language
English
LU publication?
yes
id
c705dd45-50e1-4080-9f67-37044372ed6f (old id 672526)
date added to LUP
2007-12-17 10:51:52
date last changed
2017-01-01 04:58:26
@article{c705dd45-50e1-4080-9f67-37044372ed6f,
  abstract     = {Reaction monitoring by Raman microspectroscopy in levitated room temperature ionic liquid (RTIL) droplets is reported. Due to their non-volatility, RTIL droplets are well-suited to act as wall-less microreactors. The droplets were produced by a piezoelectric flow-through microdispenser connected to an automated flow injection system and were levitated by an acoustic trap. Taking advantage of the flow system versatility, the sequence of reagents was easily changed to study a model organic reaction: the Knoevenagel condensation. The reaction was followed by Raman microspectrometry and the obtained spectra were analysed using multivariate curve resolution to retrieve the concentration profiles and pure spectra of reactants, intermediates and products involved in the reaction. In addition, information about solvation interactions was obtained by monitoring the desolvation process taking place when a volatile co-solvent evaporated from the droplet.},
  author       = {Lopez-Pastor, Mercedes and Dominguez-Vidal, Ana and Ayora-Canada, Maria Jose and Laurell, Thomas and Valcarcel, Miguel and Lendl, Bernhard},
  issn         = {1473-0189},
  language     = {eng},
  number       = {1},
  pages        = {126--132},
  publisher    = {Royal Society of Chemistry},
  series       = {Lab on A Chip},
  title        = {Containerless reaction monitoring in ionic liquids by means of Raman microspectroscopy},
  url          = {http://dx.doi.org/10.1039/b608618g},
  volume       = {7},
  year         = {2007},
}