Containerless reaction monitoring in ionic liquids by means of Raman microspectroscopy
(2007) In Lab on a Chip 7(1). p.126-132- Abstract
- Reaction monitoring by Raman microspectroscopy in levitated room temperature ionic liquid (RTIL) droplets is reported. Due to their non-volatility, RTIL droplets are well-suited to act as wall-less microreactors. The droplets were produced by a piezoelectric flow-through microdispenser connected to an automated flow injection system and were levitated by an acoustic trap. Taking advantage of the flow system versatility, the sequence of reagents was easily changed to study a model organic reaction: the Knoevenagel condensation. The reaction was followed by Raman microspectrometry and the obtained spectra were analysed using multivariate curve resolution to retrieve the concentration profiles and pure spectra of reactants, intermediates and... (More)
- Reaction monitoring by Raman microspectroscopy in levitated room temperature ionic liquid (RTIL) droplets is reported. Due to their non-volatility, RTIL droplets are well-suited to act as wall-less microreactors. The droplets were produced by a piezoelectric flow-through microdispenser connected to an automated flow injection system and were levitated by an acoustic trap. Taking advantage of the flow system versatility, the sequence of reagents was easily changed to study a model organic reaction: the Knoevenagel condensation. The reaction was followed by Raman microspectrometry and the obtained spectra were analysed using multivariate curve resolution to retrieve the concentration profiles and pure spectra of reactants, intermediates and products involved in the reaction. In addition, information about solvation interactions was obtained by monitoring the desolvation process taking place when a volatile co-solvent evaporated from the droplet. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/672526
- author
- Lopez-Pastor, Mercedes ; Dominguez-Vidal, Ana ; Ayora-Canada, Maria Jose ; Laurell, Thomas LU ; Valcarcel, Miguel and Lendl, Bernhard
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Lab on a Chip
- volume
- 7
- issue
- 1
- pages
- 126 - 132
- publisher
- Royal Society of Chemistry
- external identifiers
-
- wos:000244616200019
- scopus:33845762012
- ISSN
- 1473-0189
- DOI
- 10.1039/b608618g
- language
- English
- LU publication?
- yes
- id
- c705dd45-50e1-4080-9f67-37044372ed6f (old id 672526)
- date added to LUP
- 2016-04-01 12:14:53
- date last changed
- 2022-04-21 04:47:48
@article{c705dd45-50e1-4080-9f67-37044372ed6f, abstract = {{Reaction monitoring by Raman microspectroscopy in levitated room temperature ionic liquid (RTIL) droplets is reported. Due to their non-volatility, RTIL droplets are well-suited to act as wall-less microreactors. The droplets were produced by a piezoelectric flow-through microdispenser connected to an automated flow injection system and were levitated by an acoustic trap. Taking advantage of the flow system versatility, the sequence of reagents was easily changed to study a model organic reaction: the Knoevenagel condensation. The reaction was followed by Raman microspectrometry and the obtained spectra were analysed using multivariate curve resolution to retrieve the concentration profiles and pure spectra of reactants, intermediates and products involved in the reaction. In addition, information about solvation interactions was obtained by monitoring the desolvation process taking place when a volatile co-solvent evaporated from the droplet.}}, author = {{Lopez-Pastor, Mercedes and Dominguez-Vidal, Ana and Ayora-Canada, Maria Jose and Laurell, Thomas and Valcarcel, Miguel and Lendl, Bernhard}}, issn = {{1473-0189}}, language = {{eng}}, number = {{1}}, pages = {{126--132}}, publisher = {{Royal Society of Chemistry}}, series = {{Lab on a Chip}}, title = {{Containerless reaction monitoring in ionic liquids by means of Raman microspectroscopy}}, url = {{http://dx.doi.org/10.1039/b608618g}}, doi = {{10.1039/b608618g}}, volume = {{7}}, year = {{2007}}, }