Advanced

Dynamic extraction coupled on-line to liquid chromatography with a parallel sampling interface—a proof of concept for monitoring extraction kinetics

Sun, Mingzhe LU ; Al-hamimi, Said LU ; Sandahl, Margareta LU and Turner, Charlotta LU (2019) In Analytical and Bioanalytical Chemistry 411(16). p.3675-3683
Abstract

On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the concept of comprehensive two-dimensional chromatography. In this study, pressurised hot water extraction was coupled on-line with ultra-high-performance liquid chromatography. The set-up was utilised in a kinetic study of dynamic pressurised hot water extraction of curcuminoids from turmeric powder. Compound-specific extraction curves were... (More)

On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the concept of comprehensive two-dimensional chromatography. In this study, pressurised hot water extraction was coupled on-line with ultra-high-performance liquid chromatography. The set-up was utilised in a kinetic study of dynamic pressurised hot water extraction of curcuminoids from turmeric powder. Compound-specific extraction curves were obtained, which clearly indicated the rate-limiting factors of the extraction processes under different conditions. Additionally, thermal degradation of curcumin during the extraction could also be demonstrated in some of the extractions.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Curcuminoids, Dynamic extraction, Liquid chromatography, On-line hyphenation, Parallel sampling, Turmeric powder
in
Analytical and Bioanalytical Chemistry
volume
411
issue
16
pages
3675 - 3683
publisher
Springer
external identifiers
  • scopus:85065440341
ISSN
1618-2642
DOI
10.1007/s00216-019-01849-4
language
English
LU publication?
yes
id
672a88f9-8be9-4fad-9e67-38ff9fe7de70
date added to LUP
2019-05-27 08:27:04
date last changed
2019-06-28 11:21:06
@article{672a88f9-8be9-4fad-9e67-38ff9fe7de70,
  abstract     = {<p>On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the concept of comprehensive two-dimensional chromatography. In this study, pressurised hot water extraction was coupled on-line with ultra-high-performance liquid chromatography. The set-up was utilised in a kinetic study of dynamic pressurised hot water extraction of curcuminoids from turmeric powder. Compound-specific extraction curves were obtained, which clearly indicated the rate-limiting factors of the extraction processes under different conditions. Additionally, thermal degradation of curcumin during the extraction could also be demonstrated in some of the extractions.</p>},
  author       = {Sun, Mingzhe and Al-hamimi, Said and Sandahl, Margareta and Turner, Charlotta},
  issn         = {1618-2642},
  keyword      = {Curcuminoids,Dynamic extraction,Liquid chromatography,On-line hyphenation,Parallel sampling,Turmeric powder},
  language     = {eng},
  month        = {05},
  number       = {16},
  pages        = {3675--3683},
  publisher    = {Springer},
  series       = {Analytical and Bioanalytical Chemistry},
  title        = {Dynamic extraction coupled on-line to liquid chromatography with a parallel sampling interface—a proof of concept for monitoring extraction kinetics},
  url          = {http://dx.doi.org/10.1007/s00216-019-01849-4},
  volume       = {411},
  year         = {2019},
}