Dynamic extraction coupled on-line to liquid chromatography with a parallel sampling interface—a proof of concept for monitoring extraction kinetics
Sun, Mingzhe LU ; Al-hamimi, Said LU ; Sandahl, Margareta LU and Turner, Charlotta LU
(2019)
In Analytical and Bioanalytical Chemistry
411(16).
p.3675-3683
- Abstract
On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the concept of comprehensive two-dimensional chromatography. In this study, pressurised hot water extraction was coupled on-line with ultra-high-performance liquid chromatography. The set-up was utilised in a kinetic study of dynamic pressurised hot water extraction of curcuminoids from turmeric powder. Compound-specific extraction curves were... (More)
On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the concept of comprehensive two-dimensional chromatography. In this study, pressurised hot water extraction was coupled on-line with ultra-high-performance liquid chromatography. The set-up was utilised in a kinetic study of dynamic pressurised hot water extraction of curcuminoids from turmeric powder. Compound-specific extraction curves were obtained, which clearly indicated the rate-limiting factors of the extraction processes under different conditions. Additionally, thermal degradation of curcumin during the extraction could also be demonstrated in some of the extractions.
(Less)
- author
- Sun, Mingzhe
LU
; Al-hamimi, Said
LU
; Sandahl, Margareta
LU
and Turner, Charlotta
LU
- organization
- publishing date
- 2019-05-06
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Curcuminoids, Dynamic extraction, Liquid chromatography, On-line hyphenation, Parallel sampling, Turmeric powder
- in
- Analytical and Bioanalytical Chemistry
- volume
- 411
- issue
- 16
- pages
- 3675 - 3683
- publisher
- Springer
- external identifiers
-
- scopus:85065440341
- pmid:31062062
- ISSN
- 1618-2642
- DOI
- 10.1007/s00216-019-01849-4
- language
- English
- LU publication?
- yes
- id
- 672a88f9-8be9-4fad-9e67-38ff9fe7de70
- date added to LUP
- 2019-05-27 08:27:04
- date last changed
- 2024-10-02 02:08:51
@article{672a88f9-8be9-4fad-9e67-38ff9fe7de70,
abstract = {{<p>On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the concept of comprehensive two-dimensional chromatography. In this study, pressurised hot water extraction was coupled on-line with ultra-high-performance liquid chromatography. The set-up was utilised in a kinetic study of dynamic pressurised hot water extraction of curcuminoids from turmeric powder. Compound-specific extraction curves were obtained, which clearly indicated the rate-limiting factors of the extraction processes under different conditions. Additionally, thermal degradation of curcumin during the extraction could also be demonstrated in some of the extractions.</p>}},
author = {{Sun, Mingzhe and Al-hamimi, Said and Sandahl, Margareta and Turner, Charlotta}},
issn = {{1618-2642}},
keywords = {{Curcuminoids; Dynamic extraction; Liquid chromatography; On-line hyphenation; Parallel sampling; Turmeric powder}},
language = {{eng}},
month = {{05}},
number = {{16}},
pages = {{3675--3683}},
publisher = {{Springer}},
series = {{Analytical and Bioanalytical Chemistry}},
title = {{Dynamic extraction coupled on-line to liquid chromatography with a parallel sampling interface—a proof of concept for monitoring extraction kinetics}},
url = {{http://dx.doi.org/10.1007/s00216-019-01849-4}},
doi = {{10.1007/s00216-019-01849-4}},
volume = {{411}},
year = {{2019}},
}