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Total cholesterol, glucose, and electrolytes in piglets serum after alpha-ketoglutarate (AKG) and dexamethasone treatment during prenatal and neonatal life

Sliwa, Ewa ; Tatara, Marcin R. and Pierzynowski, Stefan LU (2006) In Bulletin of the Veterinary Institute in Puławy 50(4). p.561-566
Abstract
The aim Of this Study was to determine the effects of dexamethasone (Dex) and alpha-ketoglutarate (AKG) oil the total cholesterol, glucose, Na+, Cl-, total Ca and K+ levels, in serum for newborn and neonate piglets. The blood samples were collected from newborn non-suckling piglets born by sows administered front the 91(st) d of pregnancy to the parturition With AKG and/or Dex (AKG-0.4 g/kg b.w./every day, orally; Dex-3 mg/sow, i.m. every second day). The second blood sampling was collected front the same piglets oil the 14(th) d of their life, after further Dex and AKG administration in the same way as in sows. The serum total cholesterol level of control piglets was the highest, and reached the value of 40.6 mg%, whereas the level was... (More)
The aim Of this Study was to determine the effects of dexamethasone (Dex) and alpha-ketoglutarate (AKG) oil the total cholesterol, glucose, Na+, Cl-, total Ca and K+ levels, in serum for newborn and neonate piglets. The blood samples were collected from newborn non-suckling piglets born by sows administered front the 91(st) d of pregnancy to the parturition With AKG and/or Dex (AKG-0.4 g/kg b.w./every day, orally; Dex-3 mg/sow, i.m. every second day). The second blood sampling was collected front the same piglets oil the 14(th) d of their life, after further Dex and AKG administration in the same way as in sows. The serum total cholesterol level of control piglets was the highest, and reached the value of 40.6 mg%, whereas the level was the lowest in AKG group (27.9 mg%). The total cholesterol serum level in 14-d-old piglets in AKG+Dex and Dex groups reached 304 mg% and 273 mg%, respectively, in the AKG group only 155 mg%, while ill the controls - 197 mg%. The decreased total serum cholesterol level in newborn and neonatal piglets, after maternal and neonatal administration of AKG, indicated the same lowering effect. AKG given to sows during the last weeks of pregnancy decreased serum Na+ Cl- and K+ levels in newborns, but did not influence after further administration to piglets during their 14 d of neonatal life. Increased serum K+ and total Ca levels in 14-day-old piglets front both groups treated with Dex and AKG+Dex, and Cl- loss in Dex group were observed. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cholesterol, electrolytes, dexamethasone, pigs, alpha-ketoglutarate, glucose
in
Bulletin of the Veterinary Institute in Puławy
volume
50
issue
4
pages
561 - 566
publisher
National Veterinary Research Institute
external identifiers
  • wos:000243278300028
  • scopus:33847733043
ISSN
0042-4870
language
English
LU publication?
yes
id
0d9ad892-f9bd-445f-9578-f6292e51c922 (old id 679524)
date added to LUP
2016-04-01 17:11:01
date last changed
2020-05-20 03:04:08
@article{0d9ad892-f9bd-445f-9578-f6292e51c922,
  abstract     = {The aim Of this Study was to determine the effects of dexamethasone (Dex) and alpha-ketoglutarate (AKG) oil the total cholesterol, glucose, Na+, Cl-, total Ca and K+ levels, in serum for newborn and neonate piglets. The blood samples were collected from newborn non-suckling piglets born by sows administered front the 91(st) d of pregnancy to the parturition With AKG and/or Dex (AKG-0.4 g/kg b.w./every day, orally; Dex-3 mg/sow, i.m. every second day). The second blood sampling was collected front the same piglets oil the 14(th) d of their life, after further Dex and AKG administration in the same way as in sows. The serum total cholesterol level of control piglets was the highest, and reached the value of 40.6 mg%, whereas the level was the lowest in AKG group (27.9 mg%). The total cholesterol serum level in 14-d-old piglets in AKG+Dex and Dex groups reached 304 mg% and 273 mg%, respectively, in the AKG group only 155 mg%, while ill the controls - 197 mg%. The decreased total serum cholesterol level in newborn and neonatal piglets, after maternal and neonatal administration of AKG, indicated the same lowering effect. AKG given to sows during the last weeks of pregnancy decreased serum Na+ Cl- and K+ levels in newborns, but did not influence after further administration to piglets during their 14 d of neonatal life. Increased serum K+ and total Ca levels in 14-day-old piglets front both groups treated with Dex and AKG+Dex, and Cl- loss in Dex group were observed.},
  author       = {Sliwa, Ewa and Tatara, Marcin R. and Pierzynowski, Stefan},
  issn         = {0042-4870},
  language     = {eng},
  number       = {4},
  pages        = {561--566},
  publisher    = {National Veterinary Research Institute},
  series       = {Bulletin of the Veterinary Institute in Puławy},
  title        = {Total cholesterol, glucose, and electrolytes in piglets serum after alpha-ketoglutarate (AKG) and dexamethasone treatment during prenatal and neonatal life},
  volume       = {50},
  year         = {2006},
}