Monolithic cryogels with open porous structure and unique double-continuous macroporous networks
(2008) In Soft Matter 4(12). p.2418-2428- Abstract
- A novel approach to create macroporous cryogels (or gels synthesized at sub-zero temperatures) with increased mechanical strength is presented. The cryogels with unique double-continuous macroporous networks were prepared via sequential freezing-thawing, when the new cryogel was synthesized inside the interconnected macropores of the preformed or primary cryogel. The prepared double-continuous macroporous cryogels (DM cryogels) have continuously interlacing networks of primary cryogel with the newly synthesized cryogels visualized by confocal laser scanning microscopy and scanning electron microscopy. The open structures of the DM cryogels with up to 150-mm-sized interconnected pores and tissue-like elasticity make them attractive as... (More)
- A novel approach to create macroporous cryogels (or gels synthesized at sub-zero temperatures) with increased mechanical strength is presented. The cryogels with unique double-continuous macroporous networks were prepared via sequential freezing-thawing, when the new cryogel was synthesized inside the interconnected macropores of the preformed or primary cryogel. The prepared double-continuous macroporous cryogels (DM cryogels) have continuously interlacing networks of primary cryogel with the newly synthesized cryogels visualized by confocal laser scanning microscopy and scanning electron microscopy. The open structures of the DM cryogels with up to 150-mm-sized interconnected pores and tissue-like elasticity make them attractive as three-dimensional cell scaffolds for tissue-engineering applications. In particular, a method of preparation of macroporous cryogels with open porous structure and/or gradient porosity, increased mechanical strength and increased content of functional groups is shown. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1377521
- author
- Plieva, Fatima LU ; Ekström, Peter LU ; Galaev, Igor LU and Mattiasson, Bo LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Soft Matter
- volume
- 4
- issue
- 12
- pages
- 2418 - 2428
- publisher
- Royal Society of Chemistry
- external identifiers
-
- wos:000261726400016
- scopus:54949134900
- ISSN
- 1744-6848
- DOI
- 10.1039/b804105a
- language
- English
- LU publication?
- yes
- id
- 67c97ec0-dfab-4bf9-8790-2c9a3f8cedca (old id 1377521)
- date added to LUP
- 2016-04-01 14:24:36
- date last changed
- 2022-03-06 19:07:33
@article{67c97ec0-dfab-4bf9-8790-2c9a3f8cedca,
abstract = {{A novel approach to create macroporous cryogels (or gels synthesized at sub-zero temperatures) with increased mechanical strength is presented. The cryogels with unique double-continuous macroporous networks were prepared via sequential freezing-thawing, when the new cryogel was synthesized inside the interconnected macropores of the preformed or primary cryogel. The prepared double-continuous macroporous cryogels (DM cryogels) have continuously interlacing networks of primary cryogel with the newly synthesized cryogels visualized by confocal laser scanning microscopy and scanning electron microscopy. The open structures of the DM cryogels with up to 150-mm-sized interconnected pores and tissue-like elasticity make them attractive as three-dimensional cell scaffolds for tissue-engineering applications. In particular, a method of preparation of macroporous cryogels with open porous structure and/or gradient porosity, increased mechanical strength and increased content of functional groups is shown.}},
author = {{Plieva, Fatima and Ekström, Peter and Galaev, Igor and Mattiasson, Bo}},
issn = {{1744-6848}},
language = {{eng}},
number = {{12}},
pages = {{2418--2428}},
publisher = {{Royal Society of Chemistry}},
series = {{Soft Matter}},
title = {{Monolithic cryogels with open porous structure and unique double-continuous macroporous networks}},
url = {{http://dx.doi.org/10.1039/b804105a}},
doi = {{10.1039/b804105a}},
volume = {{4}},
year = {{2008}},
}