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Bioreactor control using a probing feeding strategy and mid-ranging control

Velut, Stéphane LU ; de Maré, Lena LU and Hagander, Per LU (2007) In Control Engineering Practice 15(2). p.135-147
Abstract
The paper presents a fed-batch fermentation technique for bioreactors operating close to their maximum oxygen transfer capacity. The method combines the advantages of the probing feeding strategy and the temperature limited fed-batch technique. When the maximum oxygen transfer capacity of the reactor is reached, the temperature is decreased to lower the oxygen demand. To achieve a good control of the dissolved oxygen a mid-ranging controller manipulating the stirrer speed and the temperature is used. The feeding strategy is analysed and it is also illustrated by simulations and an experiment. (c) 2006 Elsevier Ltd. All rights reserved.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
temperature, mid-ranging, control, dissolved oxygen, probing, fermentation processes, feeding strategy
in
Control Engineering Practice
volume
15
issue
2
pages
135 - 147
publisher
Elsevier
external identifiers
  • wos:000242760200001
  • scopus:33750145426
ISSN
0967-0661
DOI
10.1016/j.conengprac.2006.05.009
language
English
LU publication?
yes
id
7bb1be11-5059-4aca-a165-390fbf4bfcda (old id 682312)
date added to LUP
2008-01-03 11:28:17
date last changed
2017-09-10 03:37:00
@article{7bb1be11-5059-4aca-a165-390fbf4bfcda,
  abstract     = {The paper presents a fed-batch fermentation technique for bioreactors operating close to their maximum oxygen transfer capacity. The method combines the advantages of the probing feeding strategy and the temperature limited fed-batch technique. When the maximum oxygen transfer capacity of the reactor is reached, the temperature is decreased to lower the oxygen demand. To achieve a good control of the dissolved oxygen a mid-ranging controller manipulating the stirrer speed and the temperature is used. The feeding strategy is analysed and it is also illustrated by simulations and an experiment. (c) 2006 Elsevier Ltd. All rights reserved.},
  author       = {Velut, Stéphane and de Maré, Lena and Hagander, Per},
  issn         = {0967-0661},
  keyword      = {temperature,mid-ranging,control,dissolved oxygen,probing,fermentation processes,feeding strategy},
  language     = {eng},
  number       = {2},
  pages        = {135--147},
  publisher    = {Elsevier},
  series       = {Control Engineering Practice},
  title        = {Bioreactor control using a probing feeding strategy and mid-ranging control},
  url          = {http://dx.doi.org/10.1016/j.conengprac.2006.05.009},
  volume       = {15},
  year         = {2007},
}