Novel supermacroporous dextran gels
(2006) In Journal of Biomaterials Science. Polymer Edition 17(10). p.1075-1092- Abstract
- Supermacroporous dextran gels (SDGs), having pores tens of micrometers in size and highly interconnected, were prepared from dextran macromonomer through radical polymerization at subzero temperatures and compared with dextran gels prepared at ambient temperature. Dextran macromonomer was synthesized via glycidyl methacrylate derivatization of dextran T500 in DMSO medium. The derivatization of dextran was confirmed by H-1-NMR and FT-IR spectroscopy. Scanning electron microscopy revealed macropores up to 100 mu m in size. SDGs can be dried and re-swollen within seconds retaining their porous structure. The large size of interconnected pores, fast swelling and biocompatibility of dextran make SDGs promising material for tissue engineering... (More)
- Supermacroporous dextran gels (SDGs), having pores tens of micrometers in size and highly interconnected, were prepared from dextran macromonomer through radical polymerization at subzero temperatures and compared with dextran gels prepared at ambient temperature. Dextran macromonomer was synthesized via glycidyl methacrylate derivatization of dextran T500 in DMSO medium. The derivatization of dextran was confirmed by H-1-NMR and FT-IR spectroscopy. Scanning electron microscopy revealed macropores up to 100 mu m in size. SDGs can be dried and re-swollen within seconds retaining their porous structure. The large size of interconnected pores, fast swelling and biocompatibility of dextran make SDGs promising material for tissue engineering and cell culture. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/683678
- author
- Plieva, Fatima LU ; Oknianska, Alina LU ; Degerman, Eva LU ; Galaev, Igor LU and Mattiasson, Bo LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- cell, interconnected pores, swelling, dextran, supermacroporous gel, scaffolds
- in
- Journal of Biomaterials Science. Polymer Edition
- volume
- 17
- issue
- 10
- pages
- 1075 - 1092
- publisher
- VSP BV
- external identifiers
-
- wos:000242631900001
- scopus:33750098499
- ISSN
- 0920-5063
- DOI
- 10.1163/156856206778530722
- language
- English
- LU publication?
- yes
- id
- 20bf4905-d895-4e2f-9e0d-a57a24b913fc (old id 683678)
- date added to LUP
- 2016-04-01 15:31:41
- date last changed
- 2022-01-28 05:49:01
@article{20bf4905-d895-4e2f-9e0d-a57a24b913fc, abstract = {{Supermacroporous dextran gels (SDGs), having pores tens of micrometers in size and highly interconnected, were prepared from dextran macromonomer through radical polymerization at subzero temperatures and compared with dextran gels prepared at ambient temperature. Dextran macromonomer was synthesized via glycidyl methacrylate derivatization of dextran T500 in DMSO medium. The derivatization of dextran was confirmed by H-1-NMR and FT-IR spectroscopy. Scanning electron microscopy revealed macropores up to 100 mu m in size. SDGs can be dried and re-swollen within seconds retaining their porous structure. The large size of interconnected pores, fast swelling and biocompatibility of dextran make SDGs promising material for tissue engineering and cell culture.}}, author = {{Plieva, Fatima and Oknianska, Alina and Degerman, Eva and Galaev, Igor and Mattiasson, Bo}}, issn = {{0920-5063}}, keywords = {{cell; interconnected pores; swelling; dextran; supermacroporous gel; scaffolds}}, language = {{eng}}, number = {{10}}, pages = {{1075--1092}}, publisher = {{VSP BV}}, series = {{Journal of Biomaterials Science. Polymer Edition}}, title = {{Novel supermacroporous dextran gels}}, url = {{http://dx.doi.org/10.1163/156856206778530722}}, doi = {{10.1163/156856206778530722}}, volume = {{17}}, year = {{2006}}, }