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Duration of P-wave is associated with atrial fibrillation hospitalizations in patients with atrial fibrillation and paced for bradycardia

Padeletti, Luigi; Santini, Massimo; Boriani, Giuseppe; Botto, Gianluca; Ricci, Renato; Spampinato, Andrea; Vergara, Giuseppe; Rahue, Werner G.; Capucci, Alessandro and Gulizia, Michele, et al. (2007) In PACE 30(8). p.961-969
Abstract
Background: A trial fibrillation (AF) is a common problem in pacemaker patients. We conducted a prospective observational study in patients paced for bradycardia with associated paroxysmal or persistent AF, to determine whether P-wave duration may stratify patients at higher risk for AF recurrences and AF-related hospitalizations. The patients were evaluated for the prevalence, cause, and predictors of hospitalization. Methods: We studied 660 consecutive patients (50% male, 72 +/- 9 years) who received a dual-chamber pacemaker. Median value of baseline P-wave duration was equal to 100 ms (25%-75% quartile range equal to 80-120 ms). We used this cut-off to divide the patients into group A (P <= 100 ms), composed of 385 (58.3%) patients,... (More)
Background: A trial fibrillation (AF) is a common problem in pacemaker patients. We conducted a prospective observational study in patients paced for bradycardia with associated paroxysmal or persistent AF, to determine whether P-wave duration may stratify patients at higher risk for AF recurrences and AF-related hospitalizations. The patients were evaluated for the prevalence, cause, and predictors of hospitalization. Methods: We studied 660 consecutive patients (50% male, 72 +/- 9 years) who received a dual-chamber pacemaker. Median value of baseline P-wave duration was equal to 100 ms (25%-75% quartile range equal to 80-120 ms). We used this cut-off to divide the patients into group A (P <= 100 ms), composed of 385 (58.3%) patients, and group B (P > 100 ms), composed of 275 (41.7%) patients. Results: In a median follow-up of 19 months, 173 patients were hospitalized for all causes, 130 for cardiovascular causes, and 85 for AF-related hospitalizations. Multivariate logistic analysis showed that P-wave duration > 100 ms identified patients at higher risk (OR = 1.6, 95% confidence interval (1.1-2.8), P = 0.044) for AF-related hospitalizations. Patients in group B (P > 100 ms) more frequently suffered AF-related hospitalizations (16.4% vs 10.4%, P = 0.02) and underwent more frequent cardioversions (14.5% vs 9.1%, P = 0.029) compared with group A (P < 100 ms). Conclusions: P-wave duration may define the risk of persistent AFrequiring cardioversion or AF-related hospitalization in patients with a pacemaker for bradycardia with associated paroxysmal or persistent AF. (Less)
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Contribution to journal
publication status
published
subject
keywords
cardioversion, P-wave, atrial tachyarrhythmia, pacing, atrial fibrillation, electrocardiogram
in
PACE
volume
30
issue
8
pages
961 - 969
publisher
Wiley-Blackwell
external identifiers
  • wos:000248803700006
  • scopus:34547604104
ISSN
1540-8159
DOI
10.1111/j.1540-8159.2007.00793.x
language
English
LU publication?
yes
id
97f597d5-e7aa-425b-9208-270fe8fcb3d0 (old id 691395)
date added to LUP
2007-12-14 14:56:17
date last changed
2017-01-01 06:37:21
@article{97f597d5-e7aa-425b-9208-270fe8fcb3d0,
  abstract     = {Background: A trial fibrillation (AF) is a common problem in pacemaker patients. We conducted a prospective observational study in patients paced for bradycardia with associated paroxysmal or persistent AF, to determine whether P-wave duration may stratify patients at higher risk for AF recurrences and AF-related hospitalizations. The patients were evaluated for the prevalence, cause, and predictors of hospitalization. Methods: We studied 660 consecutive patients (50% male, 72 +/- 9 years) who received a dual-chamber pacemaker. Median value of baseline P-wave duration was equal to 100 ms (25%-75% quartile range equal to 80-120 ms). We used this cut-off to divide the patients into group A (P &lt;= 100 ms), composed of 385 (58.3%) patients, and group B (P &gt; 100 ms), composed of 275 (41.7%) patients. Results: In a median follow-up of 19 months, 173 patients were hospitalized for all causes, 130 for cardiovascular causes, and 85 for AF-related hospitalizations. Multivariate logistic analysis showed that P-wave duration &gt; 100 ms identified patients at higher risk (OR = 1.6, 95% confidence interval (1.1-2.8), P = 0.044) for AF-related hospitalizations. Patients in group B (P &gt; 100 ms) more frequently suffered AF-related hospitalizations (16.4% vs 10.4%, P = 0.02) and underwent more frequent cardioversions (14.5% vs 9.1%, P = 0.029) compared with group A (P &lt; 100 ms). Conclusions: P-wave duration may define the risk of persistent AFrequiring cardioversion or AF-related hospitalization in patients with a pacemaker for bradycardia with associated paroxysmal or persistent AF.},
  author       = {Padeletti, Luigi and Santini, Massimo and Boriani, Giuseppe and Botto, Gianluca and Ricci, Renato and Spampinato, Andrea and Vergara, Giuseppe and Rahue, Werner G. and Capucci, Alessandro and Gulizia, Michele and Pieragnoll, Paolo and Grammatco, M. S. Andrea and Platonov, Pyotr and Barold, S. Serge},
  issn         = {1540-8159},
  keyword      = {cardioversion,P-wave,atrial tachyarrhythmia,pacing,atrial fibrillation,electrocardiogram},
  language     = {eng},
  number       = {8},
  pages        = {961--969},
  publisher    = {Wiley-Blackwell},
  series       = {PACE},
  title        = {Duration of P-wave is associated with atrial fibrillation hospitalizations in patients with atrial fibrillation and paced for bradycardia},
  url          = {http://dx.doi.org/10.1111/j.1540-8159.2007.00793.x},
  volume       = {30},
  year         = {2007},
}