A novel hollow-fibre microporous membrane liquid-liquid extraction for determination of free 4-isobutylacetophenone concentration at ultra trace level in environmental aqueous samples
(2007) In Journal of Chromatography A 1157(1-2). p.30-37- Abstract
- In this study, a method was developed for determination of the free concentration of 4-isobutylacetophenone, a toxic degradation product of ibuprofen, in river and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up and gas chromatography-mass spectrometry (GC-MS), respectively. In this novel approach, only the liquid in the membrane pores is utilised for non-depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, and salt and humic acid content. The optimised method allowed the determination of the analyte at the ng L-1 level in river and sewage water. A linear plot gave a correlation... (More)
- In this study, a method was developed for determination of the free concentration of 4-isobutylacetophenone, a toxic degradation product of ibuprofen, in river and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up and gas chromatography-mass spectrometry (GC-MS), respectively. In this novel approach, only the liquid in the membrane pores is utilised for non-depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, and salt and humic acid content. The optimised method allowed the determination of the analyte at the ng L-1 level in river and sewage water. A linear plot gave a correlation coefficient better than 0.992 and resulted in a limit of detection of 7 and 14 ng L-1 for river and sewage water, respectively. The enrichment factor was over 2000 in the fibre and over 300 after dilution. The repeatability and reproducibility were better than 5% and 10%, respectively. For the first time, 4-isobutylacetophenone was found at free concentrations of 40 ng L-1 or below in sewage waters, while it could not be quantified in a river downstream from a municipal sewage treatment plant. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/691798
- author
- Zorita, Saioa LU ; Barri, Thaer LU and Mathiasson, Lennart LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- 4-isobutylacetophenone, free dissolved concentration, hollow-fibre microporous membrane liquid-liquid extraction, sewage water
- in
- Journal of Chromatography A
- volume
- 1157
- issue
- 1-2
- pages
- 30 - 37
- publisher
- Elsevier
- external identifiers
-
- wos:000248107200005
- scopus:34250752874
- pmid:17540383
- ISSN
- 0021-9673
- DOI
- 10.1016/j.chroma.2007.05.039
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)
- id
- d01cce52-4d3d-4d39-bde3-bc9c62765685 (old id 691798)
- date added to LUP
- 2016-04-01 17:16:08
- date last changed
- 2022-03-30 21:40:59
@article{d01cce52-4d3d-4d39-bde3-bc9c62765685,
abstract = {{In this study, a method was developed for determination of the free concentration of 4-isobutylacetophenone, a toxic degradation product of ibuprofen, in river and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up and gas chromatography-mass spectrometry (GC-MS), respectively. In this novel approach, only the liquid in the membrane pores is utilised for non-depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, and salt and humic acid content. The optimised method allowed the determination of the analyte at the ng L-1 level in river and sewage water. A linear plot gave a correlation coefficient better than 0.992 and resulted in a limit of detection of 7 and 14 ng L-1 for river and sewage water, respectively. The enrichment factor was over 2000 in the fibre and over 300 after dilution. The repeatability and reproducibility were better than 5% and 10%, respectively. For the first time, 4-isobutylacetophenone was found at free concentrations of 40 ng L-1 or below in sewage waters, while it could not be quantified in a river downstream from a municipal sewage treatment plant.}},
author = {{Zorita, Saioa and Barri, Thaer and Mathiasson, Lennart}},
issn = {{0021-9673}},
keywords = {{4-isobutylacetophenone; free dissolved concentration; hollow-fibre microporous membrane liquid-liquid extraction; sewage water}},
language = {{eng}},
number = {{1-2}},
pages = {{30--37}},
publisher = {{Elsevier}},
series = {{Journal of Chromatography A}},
title = {{A novel hollow-fibre microporous membrane liquid-liquid extraction for determination of free 4-isobutylacetophenone concentration at ultra trace level in environmental aqueous samples}},
url = {{http://dx.doi.org/10.1016/j.chroma.2007.05.039}},
doi = {{10.1016/j.chroma.2007.05.039}},
volume = {{1157}},
year = {{2007}},
}