Antisense RNAs everywhere?
(2002) In Trends in Genetics 18(5). p.223-226- Abstract
- In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded by bacterial and eukaryotic chromosomes might also belong to a ubiquitous, heterogeneous class of antisense regulators of gene expression.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/770373
- author
- Wagner, E.G.H. and Flärdh, Klas LU
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- bacteria, plasmid, riboregulator, antisense RNA, non-coding RNA, gene silencing
- in
- Trends in Genetics
- volume
- 18
- issue
- 5
- pages
- 223 - 226
- publisher
- Elsevier
- external identifiers
-
- scopus:0036575444
- ISSN
- 1362-4555
- DOI
- 10.1016/S0168-9525(02)02658-6
- language
- English
- LU publication?
- no
- id
- 6a4adf48-3c21-4d34-a24f-23dea9a88f75 (old id 770373)
- date added to LUP
- 2016-04-01 11:37:00
- date last changed
- 2022-04-20 19:19:22
@article{6a4adf48-3c21-4d34-a24f-23dea9a88f75, abstract = {{In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded by bacterial and eukaryotic chromosomes might also belong to a ubiquitous, heterogeneous class of antisense regulators of gene expression.}}, author = {{Wagner, E.G.H. and Flärdh, Klas}}, issn = {{1362-4555}}, keywords = {{bacteria; plasmid; riboregulator; antisense RNA; non-coding RNA; gene silencing}}, language = {{eng}}, number = {{5}}, pages = {{223--226}}, publisher = {{Elsevier}}, series = {{Trends in Genetics}}, title = {{Antisense RNAs everywhere?}}, url = {{http://dx.doi.org/10.1016/S0168-9525(02)02658-6}}, doi = {{10.1016/S0168-9525(02)02658-6}}, volume = {{18}}, year = {{2002}}, }