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Risk of severe COVID-19 from the Delta and Omicron variants in relation to vaccination status, sex, age and comorbidities - surveillance results from southern Sweden, July 2021 to January 2022

Kahn, Fredrik LU ; Bonander, Carl ; Moghaddassi, Mahnaz LU ; Rasmussen, Magnus LU ; Malmqvist, Ulf LU ; Inghammar, Malin LU and Björk, Jonas LU (2022) In Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 27(9).
Abstract

We compared the risk of severe COVID-19 during two periods 2021 and 2022 when Delta and Omicron, respectively, were the dominating virus variants in Scania county, Sweden. We adjusted for differences in sex, age, comorbidities, prior infection and vaccination. Risk of severe disease from Omicron was markedly lower among vaccinated cases. It was also lower among the unvaccinated but remained high (> 5%) for older people and middle-aged men with two or more comorbidities. Efforts to increase vaccination uptake should continue.

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
epidemiological surveillance, SARS-CoV-2 vaccine effectiveness, variant of concern
in
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
volume
27
issue
9
publisher
European Centre for Disease Prevention and Control (ECDC)
external identifiers
  • scopus:85125691092
  • pmid:35241215
ISSN
1560-7917
DOI
10.2807/1560-7917.ES.2022.27.9.2200121
project
Improved preparedness for future pandemics and other health crises through large-scale disease surveillance
language
English
LU publication?
yes
id
6a55f0b6-d2e3-4ef1-bedd-8d71551dad06
date added to LUP
2022-04-26 13:53:42
date last changed
2024-06-13 12:08:48
@article{6a55f0b6-d2e3-4ef1-bedd-8d71551dad06,
  abstract     = {{<p>We compared the risk of severe COVID-19 during two periods 2021 and 2022 when Delta and Omicron, respectively, were the dominating virus variants in Scania county, Sweden. We adjusted for differences in sex, age, comorbidities, prior infection and vaccination. Risk of severe disease from Omicron was markedly lower among vaccinated cases. It was also lower among the unvaccinated but remained high (&gt; 5%) for older people and middle-aged men with two or more comorbidities. Efforts to increase vaccination uptake should continue.</p>}},
  author       = {{Kahn, Fredrik and Bonander, Carl and Moghaddassi, Mahnaz and Rasmussen, Magnus and Malmqvist, Ulf and Inghammar, Malin and Björk, Jonas}},
  issn         = {{1560-7917}},
  keywords     = {{epidemiological surveillance; SARS-CoV-2 vaccine effectiveness; variant of concern}},
  language     = {{eng}},
  month        = {{03}},
  number       = {{9}},
  publisher    = {{European Centre for Disease Prevention and Control (ECDC)}},
  series       = {{Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin}},
  title        = {{Risk of severe COVID-19 from the Delta and Omicron variants in relation to vaccination status, sex, age and comorbidities - surveillance results from southern Sweden, July 2021 to January 2022}},
  url          = {{http://dx.doi.org/10.2807/1560-7917.ES.2022.27.9.2200121}},
  doi          = {{10.2807/1560-7917.ES.2022.27.9.2200121}},
  volume       = {{27}},
  year         = {{2022}},
}