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Introduction of prostate artery embolization (PAE) in Sweden

Lindgren, Hans LU and Bläckberg, Mats LU (2019) In Scandinavian Journal of Urology 53(2-3). p.151-155
Abstract

Background: Transurethral resection of the prostate (TURP) is ‘Gold Standard’ treatment for moderate-to-severe lower urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH) with bladder-outlet obstruction (BOO). However, TURP is associated with a risk of complications, so minimally invasive methods have been developed. Prostate artery embolization (PAE) is a new minimally invasive procedure. This study reports the outcomes of PAE when introduced in a ‘real life’ clinical setting in a Swedish County hospital. Methods: A prospective, single-center, single-arm study in a consecutive vascular-anatomy ‘all comers’ population, eligible for TURP or adenomaenukleation, but unsuitable for this, treated with PAE from January 2015... (More)

Background: Transurethral resection of the prostate (TURP) is ‘Gold Standard’ treatment for moderate-to-severe lower urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH) with bladder-outlet obstruction (BOO). However, TURP is associated with a risk of complications, so minimally invasive methods have been developed. Prostate artery embolization (PAE) is a new minimally invasive procedure. This study reports the outcomes of PAE when introduced in a ‘real life’ clinical setting in a Swedish County hospital. Methods: A prospective, single-center, single-arm study in a consecutive vascular-anatomy ‘all comers’ population, eligible for TURP or adenomaenukleation, but unsuitable for this, treated with PAE from January 2015 to June 2018. Defined improvement of IPSS/QoL scores, or freedom from urinary catheter if previous urinary catheter-dependent, or clean intermittent catheterization (CIC) were considered as clinically successful treatments. PAE was performed until arterial stasis using the Perfected technique. Most patients were treated during a day-care procedure. Results: Of 37 treated men, bilateral PAEs were achieved in 32 patients, unilateral PAEs in four patients, and bilateral failure in one patient due to difficult vascular anatomy. Clinically successful treatment was achieved in 84%, without serious adverse events. Conclusions: PAE was introduced in Sweden, showing PAE as a novel and good minimally invasive alternative in treatment of symptomatic BPH, possible to perform as a day-care procedure.

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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
BPH, PAE, Sweden
in
Scandinavian Journal of Urology
volume
53
issue
2-3
pages
151 - 155
publisher
Taylor & Francis
external identifiers
  • pmid:31096824
  • scopus:85066073725
ISSN
2168-1805
DOI
10.1080/21681805.2019.1610494
language
English
LU publication?
yes
id
6bee0099-5728-414c-9438-a40118b34afe
date added to LUP
2019-06-14 14:08:01
date last changed
2024-03-03 14:36:15
@article{6bee0099-5728-414c-9438-a40118b34afe,
  abstract     = {{<p>Background: Transurethral resection of the prostate (TURP) is ‘Gold Standard’ treatment for moderate-to-severe lower urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH) with bladder-outlet obstruction (BOO). However, TURP is associated with a risk of complications, so minimally invasive methods have been developed. Prostate artery embolization (PAE) is a new minimally invasive procedure. This study reports the outcomes of PAE when introduced in a ‘real life’ clinical setting in a Swedish County hospital. Methods: A prospective, single-center, single-arm study in a consecutive vascular-anatomy ‘all comers’ population, eligible for TURP or adenomaenukleation, but unsuitable for this, treated with PAE from January 2015 to June 2018. Defined improvement of IPSS/QoL scores, or freedom from urinary catheter if previous urinary catheter-dependent, or clean intermittent catheterization (CIC) were considered as clinically successful treatments. PAE was performed until arterial stasis using the Perfected technique. Most patients were treated during a day-care procedure. Results: Of 37 treated men, bilateral PAEs were achieved in 32 patients, unilateral PAEs in four patients, and bilateral failure in one patient due to difficult vascular anatomy. Clinically successful treatment was achieved in 84%, without serious adverse events. Conclusions: PAE was introduced in Sweden, showing PAE as a novel and good minimally invasive alternative in treatment of symptomatic BPH, possible to perform as a day-care procedure.</p>}},
  author       = {{Lindgren, Hans and Bläckberg, Mats}},
  issn         = {{2168-1805}},
  keywords     = {{BPH; PAE; Sweden}},
  language     = {{eng}},
  month        = {{05}},
  number       = {{2-3}},
  pages        = {{151--155}},
  publisher    = {{Taylor & Francis}},
  series       = {{Scandinavian Journal of Urology}},
  title        = {{Introduction of prostate artery embolization (PAE) in Sweden}},
  url          = {{http://dx.doi.org/10.1080/21681805.2019.1610494}},
  doi          = {{10.1080/21681805.2019.1610494}},
  volume       = {{53}},
  year         = {{2019}},
}