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Cemented versus cementless cup fixation in total hip arthroplasty for proximal femoral fractures : analysis of revision and mortality rates from the German arthroplasty registry (EPRD)

Roitzsch, Clemens ; Rogmark, Cecilia LU ; Wu, Yinan ; Grimberg, Alexander ; Lützner, Jörg and Postler, Anne (2025) In Journal of Orthopaedic Surgery and Research 20(1).
Abstract

BACKGROUND: The management of femoral neck fractures (FNF) in elderly patients depends on comorbidities, pre-fracture mobility, any hip joint disease, and life expectancy, with treatment typically involving either hemiarthroplasty (HA) or total hip arthroplasty (THA). While cemented femoral stem fixation is standard, there is no clear consensus regarding cemented versus cementless cup fixation in THA. This study aimed to compare revision and mortality rates between THA, divided into cemented and cementless cup fixation, and HA, following FNF.

METHODS: Data from the German Arthroplasty Registry (EPRD) were analyzed, including all patients with fracture-related THA or HA and available follow-up. A total of 34,501 patients undergoing... (More)

BACKGROUND: The management of femoral neck fractures (FNF) in elderly patients depends on comorbidities, pre-fracture mobility, any hip joint disease, and life expectancy, with treatment typically involving either hemiarthroplasty (HA) or total hip arthroplasty (THA). While cemented femoral stem fixation is standard, there is no clear consensus regarding cemented versus cementless cup fixation in THA. This study aimed to compare revision and mortality rates between THA, divided into cemented and cementless cup fixation, and HA, following FNF.

METHODS: Data from the German Arthroplasty Registry (EPRD) were analyzed, including all patients with fracture-related THA or HA and available follow-up. A total of 34,501 patients undergoing THA (27,757 cementless, 6,744 cemented cups) and 72,022 patients with HA were included. 5-year revision and mortality rates were compared.

RESULTS: The 5-year revision rate was the lowest in the HA group (4.1%), followed by cemented cup THA (5.0%), and cementless cup THA (6.8%; p < 0.001). Dislocation, infection, and periprosthetic fracture were the leading causes of revision. The 5-year mortality rate was the lowest in cementless cup THA patients (23%), 43% in cemented cup THA patients and highest in HA patients (54%). Cementless fixation was associated with a higher revision risk (HR 1.28, 95% CI 1.14-1.44), while HA was associated with increased mortality (HR 1.26, 95% CI 1.22-1.31).

CONCLUSION: Cemented cup fixation in THA after FNF is associated with lower revision rates but higher mortality compared to cementless fixation. In patients with limited life expectancy, HA remains the preferred option.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Orthopaedic Surgery and Research
volume
20
issue
1
article number
873
publisher
BioMed Central (BMC)
external identifiers
  • pmid:41063174
ISSN
1749-799X
DOI
10.1186/s13018-025-06281-2
language
English
LU publication?
yes
additional info
© 2025. The Author(s).
id
6c65c5e8-1b88-4582-bc91-9680fdd7db03
date added to LUP
2025-10-09 08:18:22
date last changed
2025-10-20 10:41:50
@article{6c65c5e8-1b88-4582-bc91-9680fdd7db03,
  abstract     = {{<p>BACKGROUND: The management of femoral neck fractures (FNF) in elderly patients depends on comorbidities, pre-fracture mobility, any hip joint disease, and life expectancy, with treatment typically involving either hemiarthroplasty (HA) or total hip arthroplasty (THA). While cemented femoral stem fixation is standard, there is no clear consensus regarding cemented versus cementless cup fixation in THA. This study aimed to compare revision and mortality rates between THA, divided into cemented and cementless cup fixation, and HA, following FNF.</p><p>METHODS: Data from the German Arthroplasty Registry (EPRD) were analyzed, including all patients with fracture-related THA or HA and available follow-up. A total of 34,501 patients undergoing THA (27,757 cementless, 6,744 cemented cups) and 72,022 patients with HA were included. 5-year revision and mortality rates were compared.</p><p>RESULTS: The 5-year revision rate was the lowest in the HA group (4.1%), followed by cemented cup THA (5.0%), and cementless cup THA (6.8%; p &lt; 0.001). Dislocation, infection, and periprosthetic fracture were the leading causes of revision. The 5-year mortality rate was the lowest in cementless cup THA patients (23%), 43% in cemented cup THA patients and highest in HA patients (54%). Cementless fixation was associated with a higher revision risk (HR 1.28, 95% CI 1.14-1.44), while HA was associated with increased mortality (HR 1.26, 95% CI 1.22-1.31).</p><p>CONCLUSION: Cemented cup fixation in THA after FNF is associated with lower revision rates but higher mortality compared to cementless fixation. In patients with limited life expectancy, HA remains the preferred option.</p>}},
  author       = {{Roitzsch, Clemens and Rogmark, Cecilia and Wu, Yinan and Grimberg, Alexander and Lützner, Jörg and Postler, Anne}},
  issn         = {{1749-799X}},
  language     = {{eng}},
  month        = {{10}},
  number       = {{1}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{Journal of Orthopaedic Surgery and Research}},
  title        = {{Cemented versus cementless cup fixation in total hip arthroplasty for proximal femoral fractures : analysis of revision and mortality rates from the German arthroplasty registry (EPRD)}},
  url          = {{http://dx.doi.org/10.1186/s13018-025-06281-2}},
  doi          = {{10.1186/s13018-025-06281-2}},
  volume       = {{20}},
  year         = {{2025}},
}