Viruses, diabetes, and autoimmunity : Studies of subjects at genetic risk for type 1 diabetes
Lindehammer, Sabina Resic LU and Lernmark, Åke LU
(2013)
9781461440512.
p.187-194
- Abstract
The possible importance of virus infections before the development of islet autoimmunity and then for the appearance of clinical type 1 diabetes is reviewed. There is a lack of specific data on the role of virus to induce islet autoimmunity. There is also a paucity of data to demonstrate that virus infections may contribute to an accelerated disease process resulting in clinical onset of type 1 diabetes. In contrast, there is a plethora of studies on virus infections at the time of clinical onset. However, these studies have made the understanding of virus in type 1 diabetes less easy. Future studies need to address further gestational infections and the risk of the offspring for islet autoimmunity. Such studies should also investigate... (More)
The possible importance of virus infections before the development of islet autoimmunity and then for the appearance of clinical type 1 diabetes is reviewed. There is a lack of specific data on the role of virus to induce islet autoimmunity. There is also a paucity of data to demonstrate that virus infections may contribute to an accelerated disease process resulting in clinical onset of type 1 diabetes. In contrast, there is a plethora of studies on virus infections at the time of clinical onset. However, these studies have made the understanding of virus in type 1 diabetes less easy. Future studies need to address further gestational infections and the risk of the offspring for islet autoimmunity. Such studies should also investigate the mechanisms by which gestational infections may alter the ability of the offspring to respond to future virus infections related to the development of islet autoimmunity or accelerator of the clinical onset of diabetes.
(Less)
- author
- Lindehammer, Sabina Resic
LU
and Lernmark, Åke
LU
- organization
- publishing date
- 2013
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- Diabetes and Viruses
- editor
- Taylor, K. ; Hyöty, H. ; Toniolo, A. and Zuckerman, A. J.
- volume
- 9781461440512
- pages
- 8 pages
- publisher
- Springer
- external identifiers
-
- scopus:84949180203
- ISBN
- 9781461440505
- 9781461440512
- DOI
- 10.1007/978-1-4614-4051-2_19
- language
- English
- LU publication?
- yes
- id
- 6cdec998-f578-47b6-a744-03bdbd7300fb
- date added to LUP
- 2017-09-07 11:42:35
- date last changed
- 2024-03-13 08:16:05
@inbook{6cdec998-f578-47b6-a744-03bdbd7300fb,
abstract = {{<p>The possible importance of virus infections before the development of islet autoimmunity and then for the appearance of clinical type 1 diabetes is reviewed. There is a lack of specific data on the role of virus to induce islet autoimmunity. There is also a paucity of data to demonstrate that virus infections may contribute to an accelerated disease process resulting in clinical onset of type 1 diabetes. In contrast, there is a plethora of studies on virus infections at the time of clinical onset. However, these studies have made the understanding of virus in type 1 diabetes less easy. Future studies need to address further gestational infections and the risk of the offspring for islet autoimmunity. Such studies should also investigate the mechanisms by which gestational infections may alter the ability of the offspring to respond to future virus infections related to the development of islet autoimmunity or accelerator of the clinical onset of diabetes.</p>}},
author = {{Lindehammer, Sabina Resic and Lernmark, Åke}},
booktitle = {{Diabetes and Viruses}},
editor = {{Taylor, K. and Hyöty, H. and Toniolo, A. and Zuckerman, A. J.}},
isbn = {{9781461440505}},
language = {{eng}},
pages = {{187--194}},
publisher = {{Springer}},
title = {{Viruses, diabetes, and autoimmunity : Studies of subjects at genetic risk for type 1 diabetes}},
url = {{http://dx.doi.org/10.1007/978-1-4614-4051-2_19}},
doi = {{10.1007/978-1-4614-4051-2_19}},
volume = {{9781461440512}},
year = {{2013}},
}