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Three-year recurrence of Dupuytren’s contracture after needle fasciotomy and collagenase injection : a two-centre randomized controlled trial

Scherman, Peter LU ; Jenmalm, Per and Dahlin, Lars B. LU (2018) In Journal of Hand Surgery: European Volume 43(8). p.836-840
Abstract

Collagenase injection and needle fasciotomy have similar short-term outcomes in the treatment of Dupuytren’s contracture. The purpose of this study was to compare the recurrence rate of these two procedures 3 years after index treatment of primary disease. We enrolled 93 patients (96 rays) from a previous two-centre randomized controlled trial. The rays that had been retreated or showed an increase in the total passive extension deficit of 30° or more compared with 3 months after treatment were regarded as recurrences. Seventeen of 40 needle fasciectomies and 12 of 36 of collagenase injections had recurred. This difference was not statistically significant. We conclude that collagenase injection and needle fasciotomy have similar 3-year... (More)

Collagenase injection and needle fasciotomy have similar short-term outcomes in the treatment of Dupuytren’s contracture. The purpose of this study was to compare the recurrence rate of these two procedures 3 years after index treatment of primary disease. We enrolled 93 patients (96 rays) from a previous two-centre randomized controlled trial. The rays that had been retreated or showed an increase in the total passive extension deficit of 30° or more compared with 3 months after treatment were regarded as recurrences. Seventeen of 40 needle fasciectomies and 12 of 36 of collagenase injections had recurred. This difference was not statistically significant. We conclude that collagenase injection and needle fasciotomy have similar 3-year recurrence rates in the treatment of Dupuytren’s contracture. Level of evidence: I.

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author
organization
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type
Contribution to journal
publication status
published
subject
keywords
collagenase injection, Dupuytren’s disease, needle fasciotomy, randomized controlled trial, recurrence rate
in
Journal of Hand Surgery: European Volume
volume
43
issue
8
pages
836 - 840
publisher
SAGE Publications Inc.
external identifiers
  • scopus:85050246337
ISSN
1753-1934
DOI
10.1177/1753193418786947
language
English
LU publication?
yes
id
6d57518c-3c8e-46e2-a62e-9fa6dd745ed4
date added to LUP
2018-09-24 14:10:26
date last changed
2019-01-14 08:39:41
@article{6d57518c-3c8e-46e2-a62e-9fa6dd745ed4,
  abstract     = {<p>Collagenase injection and needle fasciotomy have similar short-term outcomes in the treatment of Dupuytren’s contracture. The purpose of this study was to compare the recurrence rate of these two procedures 3 years after index treatment of primary disease. We enrolled 93 patients (96 rays) from a previous two-centre randomized controlled trial. The rays that had been retreated or showed an increase in the total passive extension deficit of 30° or more compared with 3 months after treatment were regarded as recurrences. Seventeen of 40 needle fasciectomies and 12 of 36 of collagenase injections had recurred. This difference was not statistically significant. We conclude that collagenase injection and needle fasciotomy have similar 3-year recurrence rates in the treatment of Dupuytren’s contracture. Level of evidence: I.</p>},
  author       = {Scherman, Peter and Jenmalm, Per and Dahlin, Lars B.},
  issn         = {1753-1934},
  keyword      = {collagenase injection,Dupuytren’s disease,needle fasciotomy,randomized controlled trial,recurrence rate},
  language     = {eng},
  month        = {07},
  number       = {8},
  pages        = {836--840},
  publisher    = {SAGE Publications Inc.},
  series       = {Journal of Hand Surgery: European Volume},
  title        = {Three-year recurrence of Dupuytren’s contracture after needle fasciotomy and collagenase injection : a two-centre randomized controlled trial},
  url          = {http://dx.doi.org/10.1177/1753193418786947},
  volume       = {43},
  year         = {2018},
}