Quantifying the absorption and reduced scattering coefficients of tissuelike turbid media over a broad spectral range with noncontact Fourier-transform hyperspectral imaging
(2000) In Applied Optics 39(34). p.6487-6497- Abstract
- Absorption (mu (a)) and reduced scattering (mu (s)') spectra of turbid media were quanti fied with a noncontact imaging approach based on a Fourier-transform interferometric imaging system (FTIIS). The FTIIS was used to collect hyperspectral images of the steady-state diffuse reflectance from turbid media. Spatially resolved reflectance data from Monte Carlo simulations were fitted to the recorded hyperspectral images to quantify mu (a) and mu (s)' spectra in the 550-850-nm region. A simple and effective calibration approach was introduced to account for the instrument response. With reflectance data that were close to and far from the source (0.5-6.5 mm), mu (a) and mu (')(s) of homogeneous, semi-infinite turbid phantoms with optical... (More)
- Absorption (mu (a)) and reduced scattering (mu (s)') spectra of turbid media were quanti fied with a noncontact imaging approach based on a Fourier-transform interferometric imaging system (FTIIS). The FTIIS was used to collect hyperspectral images of the steady-state diffuse reflectance from turbid media. Spatially resolved reflectance data from Monte Carlo simulations were fitted to the recorded hyperspectral images to quantify mu (a) and mu (s)' spectra in the 550-850-nm region. A simple and effective calibration approach was introduced to account for the instrument response. With reflectance data that were close to and far from the source (0.5-6.5 mm), mu (a) and mu (')(s) of homogeneous, semi-infinite turbid phantoms with optical property ranges comparable with those of tissues were determined with an accuracy of +/-7% and +/-3%, respectively. Prediction accuracy for mu (a) and mu (s)' degraded to +/-12% and +/-4%, respectively, when only reflectance data close to the source (0.5-2.5 mm) were used. Results indicate that reflectance data close to and far hom the source are necessary for optimal quantification of mu (a) and mu (s)'. The spectral properties of mu (a) and mu (s)' values were used to determine the concentrations of absorbers and scatterers, respectively. Absorber and scatterer concentrations of two-chromophore turbid media were determined with an accuracy of +/-5% and +/-3%, respectively. (C) 2000 Optical Society of America OCIS codes: 170.0110, 170.7050, 170.6510, 070.2590, 120.3180. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2259154
- author
- Pham, T. H ; Bevilacqua, F ; Spott, T ; Dam, J. S ; Tromberg, B. J and Andersson-Engels, Stefan LU
- organization
- publishing date
- 2000
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied Optics
- volume
- 39
- issue
- 34
- pages
- 6487 - 6497
- publisher
- Optical Society of America
- external identifiers
-
- scopus:0001338996
- ISSN
- 2155-3165
- DOI
- 10.1364/AO.39.006487
- language
- English
- LU publication?
- yes
- id
- 6e3abcf7-5e39-4346-916c-8e0da20a6cab (old id 2259154)
- date added to LUP
- 2016-04-04 08:21:56
- date last changed
- 2022-02-13 06:10:16
@article{6e3abcf7-5e39-4346-916c-8e0da20a6cab,
abstract = {{Absorption (mu (a)) and reduced scattering (mu (s)') spectra of turbid media were quanti fied with a noncontact imaging approach based on a Fourier-transform interferometric imaging system (FTIIS). The FTIIS was used to collect hyperspectral images of the steady-state diffuse reflectance from turbid media. Spatially resolved reflectance data from Monte Carlo simulations were fitted to the recorded hyperspectral images to quantify mu (a) and mu (s)' spectra in the 550-850-nm region. A simple and effective calibration approach was introduced to account for the instrument response. With reflectance data that were close to and far from the source (0.5-6.5 mm), mu (a) and mu (')(s) of homogeneous, semi-infinite turbid phantoms with optical property ranges comparable with those of tissues were determined with an accuracy of +/-7% and +/-3%, respectively. Prediction accuracy for mu (a) and mu (s)' degraded to +/-12% and +/-4%, respectively, when only reflectance data close to the source (0.5-2.5 mm) were used. Results indicate that reflectance data close to and far hom the source are necessary for optimal quantification of mu (a) and mu (s)'. The spectral properties of mu (a) and mu (s)' values were used to determine the concentrations of absorbers and scatterers, respectively. Absorber and scatterer concentrations of two-chromophore turbid media were determined with an accuracy of +/-5% and +/-3%, respectively. (C) 2000 Optical Society of America OCIS codes: 170.0110, 170.7050, 170.6510, 070.2590, 120.3180.}},
author = {{Pham, T. H and Bevilacqua, F and Spott, T and Dam, J. S and Tromberg, B. J and Andersson-Engels, Stefan}},
issn = {{2155-3165}},
language = {{eng}},
number = {{34}},
pages = {{6487--6497}},
publisher = {{Optical Society of America}},
series = {{Applied Optics}},
title = {{Quantifying the absorption and reduced scattering coefficients of tissuelike turbid media over a broad spectral range with noncontact Fourier-transform hyperspectral imaging}},
url = {{https://lup.lub.lu.se/search/files/5177218/2297521.pdf}},
doi = {{10.1364/AO.39.006487}},
volume = {{39}},
year = {{2000}},
}