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Diagnosis and treatment of brain metastases from solid tumors : Guidelines from the European Association of neuro-oncology (EANO)

Soffietti, Riccardo; Abacioglu, Ufuk; Baumert, Brigitta; Combs, Stephanie E.; Kinhult, Sara LU ; Kros, Johan M.; Marosi, Christine; Metellus, Philippe; Radbruch, Alexander and Freixa, Salvador S.Villa, et al. (2017) In Neuro-Oncology 19(2). p.162-174
Abstract

The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy... (More)

The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.

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Please use this url to cite or link to this publication:
@article{6fe26477-7597-44dd-8f60-ebaae7b42573,
  abstract     = {<p>The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.</p>},
  author       = {Soffietti, Riccardo and Abacioglu, Ufuk and Baumert, Brigitta and Combs, Stephanie E. and Kinhult, Sara and Kros, Johan M. and Marosi, Christine and Metellus, Philippe and Radbruch, Alexander and Freixa, Salvador S.Villa and Brada, Michael and Carapella, Carmine M. and Preusser, Matthias and Le Rhun, Emilie and Rudà, Roberta and Tonn, Joerg C. and Weber, Damien C. and Weller, Michael},
  issn         = {1522-8517},
  keyword      = {Brain metastases,Chemotherapy,Neuroimaging,Neuropathology,Stereotactic radiosurgery/stereotactic fractionated radiotherapy,Supportive care,Surgery,Targeted therapy,Whole-brain radiation therapy},
  language     = {eng},
  number       = {2},
  pages        = {162--174},
  publisher    = {Oxford University Press},
  series       = {Neuro-Oncology},
  title        = {Diagnosis and treatment of brain metastases from solid tumors : Guidelines from the European Association of neuro-oncology (EANO)},
  url          = {http://dx.doi.org/10.1093/neuonc/now241},
  volume       = {19},
  year         = {2017},
}