Emerging Imaging Technologies for Parathyroid Gland Identification and Vascular Assessment in Thyroid Surgery : A Review from the American Head and Neck Society Endocrine Surgery Section
(2023) In JAMA Otolaryngology - Head and Neck Surgery 149(3). p.253-260- Abstract
Importance: Identification and preservation of parathyroid glands (PGs) remain challenging despite advances in surgical techniques. Considerable morbidity and even mortality result from hypoparathyroidism caused by devascularization or inadvertent removal of PGs. Emerging imaging technologies hold promise to improve identification and preservation of PGs during thyroid surgery. Observation: This narrative review (1) comprehensively reviews PG identification and vascular assessment using near-infrared autofluorescence (NIRAF) - both label free and in combination with indocyanine green - based on a comprehensive literature review and (2) offers a manual for possible implementation these emerging technologies in thyroid surgery.... (More)
Importance: Identification and preservation of parathyroid glands (PGs) remain challenging despite advances in surgical techniques. Considerable morbidity and even mortality result from hypoparathyroidism caused by devascularization or inadvertent removal of PGs. Emerging imaging technologies hold promise to improve identification and preservation of PGs during thyroid surgery. Observation: This narrative review (1) comprehensively reviews PG identification and vascular assessment using near-infrared autofluorescence (NIRAF) - both label free and in combination with indocyanine green - based on a comprehensive literature review and (2) offers a manual for possible implementation these emerging technologies in thyroid surgery. Conclusions and Relevance: Emerging technologies hold promise to improve PG identification and preservation during thyroidectomy. Future research should address variables affecting the degree of fluorescence in NIRAF, standardization of signal quantification, definitions and standardization of parameters of indocyanine green injection that correlate with postoperative PG function, the financial effect of these emerging technologies on near-term and longer-term costs, the adoption learning curve and effect on surgical training, and long-term outcomes of key quality metrics in adequately powered randomized clinical trials evaluating PG preservation.
(Less)
- author
- organization
- publishing date
- 2023-03-09
- type
- Contribution to journal
- publication status
- published
- subject
- in
- JAMA Otolaryngology - Head and Neck Surgery
- volume
- 149
- issue
- 3
- pages
- 8 pages
- publisher
- American Medical Association
- external identifiers
-
- pmid:36633855
- scopus:85149911297
- ISSN
- 2168-6181
- DOI
- 10.1001/jamaoto.2022.4421
- language
- English
- LU publication?
- yes
- id
- 70c80511-04b9-462e-81c7-40c09e1de9d8
- date added to LUP
- 2023-05-05 09:03:11
- date last changed
- 2024-09-07 10:45:52
@article{70c80511-04b9-462e-81c7-40c09e1de9d8,
abstract = {{<p>Importance: Identification and preservation of parathyroid glands (PGs) remain challenging despite advances in surgical techniques. Considerable morbidity and even mortality result from hypoparathyroidism caused by devascularization or inadvertent removal of PGs. Emerging imaging technologies hold promise to improve identification and preservation of PGs during thyroid surgery. Observation: This narrative review (1) comprehensively reviews PG identification and vascular assessment using near-infrared autofluorescence (NIRAF) - both label free and in combination with indocyanine green - based on a comprehensive literature review and (2) offers a manual for possible implementation these emerging technologies in thyroid surgery. Conclusions and Relevance: Emerging technologies hold promise to improve PG identification and preservation during thyroidectomy. Future research should address variables affecting the degree of fluorescence in NIRAF, standardization of signal quantification, definitions and standardization of parameters of indocyanine green injection that correlate with postoperative PG function, the financial effect of these emerging technologies on near-term and longer-term costs, the adoption learning curve and effect on surgical training, and long-term outcomes of key quality metrics in adequately powered randomized clinical trials evaluating PG preservation.</p>}},
author = {{Silver Karcioglu, Amanda L. and Triponez, Frédéric and Solórzano, Carmen C. and Iwata, Ayaka J. and Abdelhamid Ahmed, Amr H. and Almquist, Martin and Angelos, Peter and Benmiloud, Fares and Berber, Eren and Bergenfelz, Anders and Cha, Jaepyeong and Colaianni, C. Alessandra and Davies, Louise and Duh, Quan Yang and Hartl, Dana and Kandil, Emad and Kim, Wan Wook and Kopp, Peter A. and Liddy, Whitney and Mahadevan-Jansen, Anita and Lee, Kang Dae and Mannstadt, Michael and McMullen, Caitlin P. and Shonka, David C. and Shin, Jennifer J. and Singer, Michael C. and Slough, Cristian M. and Stack, Brendan C. and Tearney, Guillermo and Thomas, Giju and Tolley, Neil and Vidal-Fortuny, Jordi and Randolph, Gregory W.}},
issn = {{2168-6181}},
language = {{eng}},
month = {{03}},
number = {{3}},
pages = {{253--260}},
publisher = {{American Medical Association}},
series = {{JAMA Otolaryngology - Head and Neck Surgery}},
title = {{Emerging Imaging Technologies for Parathyroid Gland Identification and Vascular Assessment in Thyroid Surgery : A Review from the American Head and Neck Society Endocrine Surgery Section}},
url = {{http://dx.doi.org/10.1001/jamaoto.2022.4421}},
doi = {{10.1001/jamaoto.2022.4421}},
volume = {{149}},
year = {{2023}},
}