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Andfåddhet potentiellt allvarligt – kräver strukturerad utredning

Ahmed, Salaheldin LU orcid ; Ahmed, Abdulla LU orcid and Rådegran, Göran LU (2022) In Lakartidningen 119.
Abstract

Dyspnea is a common distressing symptom which may be a sign of a critically threatening condition and has been linked with increased hospitalizations, reduced exercise tolerance and increased mortality. The current neuropsychological model suggests that dyspnea arises due to an imbalance between respiratory drive and achieved ventilation. Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are rare but detrimental conditions, with high morbidity and mortality, where early diagnosis and treatment initiation significantly improve outcome. These conditions are often accompanied by a diagnostic delay, which for PAH has not improved since the 1980s, underlining the importance of early evaluation... (More)

Dyspnea is a common distressing symptom which may be a sign of a critically threatening condition and has been linked with increased hospitalizations, reduced exercise tolerance and increased mortality. The current neuropsychological model suggests that dyspnea arises due to an imbalance between respiratory drive and achieved ventilation. Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are rare but detrimental conditions, with high morbidity and mortality, where early diagnosis and treatment initiation significantly improve outcome. These conditions are often accompanied by a diagnostic delay, which for PAH has not improved since the 1980s, underlining the importance of early evaluation and referral to specialists. In the present work, differential diagnoses of dyspnea are discussed along with a proposal on how a structured evaluation should be performed early to minimize the diagnostic delay in PAH and CTEPH and improve outcome.

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Abstract (Swedish)
Andfåddhet är en subjektiv upplevelse och utgör ett ospecifikt, vanligt och potentiellt allvarligt symtom som tidigt bör utredas strukturerat tills orsaken är klarlagd, med fokus på att utesluta allvarliga differentialdiagnoser.

Ökad medvetenhet om allvarlighetsgraden av andfåddhet kan minska fördröjning till diagnos samt förbättra prognosen, inte minst vid sällsynta sjukdomar såsom PAH (pulmonell arteriell hypertension) och CTEPH (kronisk tromboembolisk pulmonell hypertension).

Remiss till/kontakt med specialistcentrum, och specifikt universitetssjukhusens centrum för pulmonell hypertension, vid misstanke om PAH eller CTEPH är av största vikt om diagnos inte kan fastställas efter adekvat initial utredning.
Please use this url to cite or link to this publication:
author
; and
organization
alternative title
Structured evaluation of unclear dyspnea - of great importance to early identify patients with PAH and CTEPH and improve prognosis
publishing date
type
Contribution to journal
publication status
published
subject
in
Lakartidningen
volume
119
article number
21238
publisher
Swedish Medical Association
external identifiers
  • pmid:36200267
  • scopus:85139293827
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
72077a25-b5fe-4c14-a73e-3c2b0bcaff6f
alternative location
https://lakartidningen.se/wp-content/uploads/2022/09/21238.pdf
date added to LUP
2022-12-14 09:18:51
date last changed
2024-04-14 10:18:54
@article{72077a25-b5fe-4c14-a73e-3c2b0bcaff6f,
  abstract     = {{<p>Dyspnea is a common distressing symptom which may be a sign of a critically threatening condition and has been linked with increased hospitalizations, reduced exercise tolerance and increased mortality. The current neuropsychological model suggests that dyspnea arises due to an imbalance between respiratory drive and achieved ventilation. Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are rare but detrimental conditions, with high morbidity and mortality, where early diagnosis and treatment initiation significantly improve outcome. These conditions are often accompanied by a diagnostic delay, which for PAH has not improved since the 1980s, underlining the importance of early evaluation and referral to specialists. In the present work, differential diagnoses of dyspnea are discussed along with a proposal on how a structured evaluation should be performed early to minimize the diagnostic delay in PAH and CTEPH and improve outcome.</p>}},
  author       = {{Ahmed, Salaheldin and Ahmed, Abdulla and Rådegran, Göran}},
  issn         = {{0023-7205}},
  language     = {{swe}},
  month        = {{10}},
  publisher    = {{Swedish Medical Association}},
  series       = {{Lakartidningen}},
  title        = {{Andfåddhet potentiellt allvarligt – kräver strukturerad utredning}},
  url          = {{https://lakartidningen.se/wp-content/uploads/2022/09/21238.pdf}},
  volume       = {{119}},
  year         = {{2022}},
}