Andfåddhet potentiellt allvarligt – kräver strukturerad utredning
(2022) In Lakartidningen 119.- Abstract
Dyspnea is a common distressing symptom which may be a sign of a critically threatening condition and has been linked with increased hospitalizations, reduced exercise tolerance and increased mortality. The current neuropsychological model suggests that dyspnea arises due to an imbalance between respiratory drive and achieved ventilation. Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are rare but detrimental conditions, with high morbidity and mortality, where early diagnosis and treatment initiation significantly improve outcome. These conditions are often accompanied by a diagnostic delay, which for PAH has not improved since the 1980s, underlining the importance of early evaluation... (More)
Dyspnea is a common distressing symptom which may be a sign of a critically threatening condition and has been linked with increased hospitalizations, reduced exercise tolerance and increased mortality. The current neuropsychological model suggests that dyspnea arises due to an imbalance between respiratory drive and achieved ventilation. Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are rare but detrimental conditions, with high morbidity and mortality, where early diagnosis and treatment initiation significantly improve outcome. These conditions are often accompanied by a diagnostic delay, which for PAH has not improved since the 1980s, underlining the importance of early evaluation and referral to specialists. In the present work, differential diagnoses of dyspnea are discussed along with a proposal on how a structured evaluation should be performed early to minimize the diagnostic delay in PAH and CTEPH and improve outcome.
(Less)- Abstract (Swedish)
- Andfåddhet är en subjektiv upplevelse och utgör ett ospecifikt, vanligt och potentiellt allvarligt symtom som tidigt bör utredas strukturerat tills orsaken är klarlagd, med fokus på att utesluta allvarliga differentialdiagnoser.
Ökad medvetenhet om allvarlighetsgraden av andfåddhet kan minska fördröjning till diagnos samt förbättra prognosen, inte minst vid sällsynta sjukdomar såsom PAH (pulmonell arteriell hypertension) och CTEPH (kronisk tromboembolisk pulmonell hypertension).
Remiss till/kontakt med specialistcentrum, och specifikt universitetssjukhusens centrum för pulmonell hypertension, vid misstanke om PAH eller CTEPH är av största vikt om diagnos inte kan fastställas efter adekvat initial utredning.
- author
- Ahmed, Salaheldin LU ; Ahmed, Abdulla LU and Rådegran, Göran LU
- organization
- alternative title
- Structured evaluation of unclear dyspnea - of great importance to early identify patients with PAH and CTEPH and improve prognosis
- publishing date
- 2022-10-05
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Lakartidningen
- volume
- 119
- article number
- 21238
- publisher
- Swedish Medical Association
- external identifiers
-
- pmid:36200267
- scopus:85139293827
- ISSN
- 0023-7205
- language
- Swedish
- LU publication?
- yes
- id
- 72077a25-b5fe-4c14-a73e-3c2b0bcaff6f
- alternative location
- https://lakartidningen.se/wp-content/uploads/2022/09/21238.pdf
- date added to LUP
- 2022-12-14 09:18:51
- date last changed
- 2024-04-14 10:18:54
@article{72077a25-b5fe-4c14-a73e-3c2b0bcaff6f, abstract = {{<p>Dyspnea is a common distressing symptom which may be a sign of a critically threatening condition and has been linked with increased hospitalizations, reduced exercise tolerance and increased mortality. The current neuropsychological model suggests that dyspnea arises due to an imbalance between respiratory drive and achieved ventilation. Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are rare but detrimental conditions, with high morbidity and mortality, where early diagnosis and treatment initiation significantly improve outcome. These conditions are often accompanied by a diagnostic delay, which for PAH has not improved since the 1980s, underlining the importance of early evaluation and referral to specialists. In the present work, differential diagnoses of dyspnea are discussed along with a proposal on how a structured evaluation should be performed early to minimize the diagnostic delay in PAH and CTEPH and improve outcome.</p>}}, author = {{Ahmed, Salaheldin and Ahmed, Abdulla and Rådegran, Göran}}, issn = {{0023-7205}}, language = {{swe}}, month = {{10}}, publisher = {{Swedish Medical Association}}, series = {{Lakartidningen}}, title = {{Andfåddhet potentiellt allvarligt – kräver strukturerad utredning}}, url = {{https://lakartidningen.se/wp-content/uploads/2022/09/21238.pdf}}, volume = {{119}}, year = {{2022}}, }