Elevated triiodothyronine in psychopathy - possible physiological mechanisms
(2004) In Journal of Neural Transmission 111(6). p.739-744- Abstract
- We assessed a total range of peripheral thyroid hormone fractions, binding globulins, and thyroid-active antibodies in 37 medication-free, violent or sexual offenders, aged 17-45 years, to describe possible mechanisms involved in the thyroid metabolism of aggressive men. The ratio between T3 and T4 correlated with ratings of psychopathy, indicating increased peripheral deiodination as a biological covariate to callous personality traits. Autoimmune antibodies, hepatic failure, abnormal binding globulins, or substance abuse did not affect the association.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1129393
- author
- Söderström, Henrik LU and Forsman, A
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Thyroid, deiodination, antibodies, aggression, violent offenders, PCL-R psychopathy
- in
- Journal of Neural Transmission
- volume
- 111
- issue
- 6
- pages
- 739 - 744
- publisher
- Springer
- external identifiers
-
- pmid:15168221
- scopus:2642530535
- ISSN
- 0300-9564
- DOI
- 10.1007/s00702-004-0137-8
- language
- English
- LU publication?
- no
- id
- 7243d8e2-439b-4d14-8ec2-f3541a35aba8 (old id 1129393)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/15168221
- http://link.springer.com/article/10.1007%2Fs00702-004-0137-8
- date added to LUP
- 2016-04-01 15:44:54
- date last changed
- 2022-01-28 06:49:32
@article{7243d8e2-439b-4d14-8ec2-f3541a35aba8,
abstract = {{We assessed a total range of peripheral thyroid hormone fractions, binding globulins, and thyroid-active antibodies in 37 medication-free, violent or sexual offenders, aged 17-45 years, to describe possible mechanisms involved in the thyroid metabolism of aggressive men. The ratio between T3 and T4 correlated with ratings of psychopathy, indicating increased peripheral deiodination as a biological covariate to callous personality traits. Autoimmune antibodies, hepatic failure, abnormal binding globulins, or substance abuse did not affect the association.}},
author = {{Söderström, Henrik and Forsman, A}},
issn = {{0300-9564}},
keywords = {{Thyroid; deiodination; antibodies; aggression; violent offenders; PCL-R psychopathy}},
language = {{eng}},
number = {{6}},
pages = {{739--744}},
publisher = {{Springer}},
series = {{Journal of Neural Transmission}},
title = {{Elevated triiodothyronine in psychopathy - possible physiological mechanisms}},
url = {{http://dx.doi.org/10.1007/s00702-004-0137-8}},
doi = {{10.1007/s00702-004-0137-8}},
volume = {{111}},
year = {{2004}},
}