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Cyclin e overexpression reduces infiltrative growth in breast cancer - Yet another link between proliferation control and tumor invasion

Berglund, Pontus LU and Landberg, Göran LU (2006) In Cell Cycle 5(6). p.606-609
Abstract
Overexpression of cyclin E is strongly linked to an aggressive phenotype and poor prognosis in breast cancer. Unexpectedly, it has been shown that cyclin E overexpression decreases mobility and invasiveness of breast cancer cells. In fact, in a study of 985 breast cancers, cyclin E correlated with less infiltrative growth. This suggests a novel function for cyclin E in breast cancer tumorigenesis and a mutual control of proliferation and invasive behavior.
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
medullary breast, proliferation, invasion, breast cancer, cyclin E, microarray, cancer
in
Cell Cycle
volume
5
issue
6
pages
606 - 609
publisher
Landes Bioscience
external identifiers
  • pmid:16582601
  • wos:000238282400015
  • scopus:33645310632
ISSN
1551-4005
language
English
LU publication?
yes
id
73480504-3aab-46cb-82a4-5f52a8256f70 (old id 406224)
alternative location
http://www.landesbioscience.com/journals/cc/abstract.php?id=2569
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16582601&dopt=Abstract
date added to LUP
2016-04-01 11:34:42
date last changed
2025-10-14 12:38:02
@article{73480504-3aab-46cb-82a4-5f52a8256f70,
  abstract     = {{Overexpression of cyclin E is strongly linked to an aggressive phenotype and poor prognosis in breast cancer. Unexpectedly, it has been shown that cyclin E overexpression decreases mobility and invasiveness of breast cancer cells. In fact, in a study of 985 breast cancers, cyclin E correlated with less infiltrative growth. This suggests a novel function for cyclin E in breast cancer tumorigenesis and a mutual control of proliferation and invasive behavior.}},
  author       = {{Berglund, Pontus and Landberg, Göran}},
  issn         = {{1551-4005}},
  keywords     = {{medullary breast; proliferation; invasion; breast cancer; cyclin E; microarray; cancer}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{606--609}},
  publisher    = {{Landes Bioscience}},
  series       = {{Cell Cycle}},
  title        = {{Cyclin e overexpression reduces infiltrative growth in breast cancer - Yet another link between proliferation control and tumor invasion}},
  url          = {{http://www.landesbioscience.com/journals/cc/abstract.php?id=2569}},
  volume       = {{5}},
  year         = {{2006}},
}