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Transfer of vertical nanowire arrays on polycaprolactone substrates for biological applications

von Ahnen, Inga; Piret, Gaelle LU and Prinz, Christelle LU (2015) In Microelectronic Engineering 135. p.52-56
Abstract
We used two methods, namely stamping and printing, to transfer arrays of epitaxial gallium phosphide (Gap) nanowires from their growth substrate to a soft, biodegradable layer of polycaprolactone (PCL). Using the stamping method resulted in a very inhomogeneous surface topography with a wide distribution of transferred nanowire lengths, whereas using the printing method resulted in an homogeneous substrate topography over several mm(2). PC12 cells were cultured on the hybrid nanowire-PCL substrates realized using the printing method and exhibited an increased attachment on these substrates, compared to the original nanowire-semiconductor substrate. Transferring nanowires on PCL substrates is promising for implanting nanowires in-vivo with... (More)
We used two methods, namely stamping and printing, to transfer arrays of epitaxial gallium phosphide (Gap) nanowires from their growth substrate to a soft, biodegradable layer of polycaprolactone (PCL). Using the stamping method resulted in a very inhomogeneous surface topography with a wide distribution of transferred nanowire lengths, whereas using the printing method resulted in an homogeneous substrate topography over several mm(2). PC12 cells were cultured on the hybrid nanowire-PCL substrates realized using the printing method and exhibited an increased attachment on these substrates, compared to the original nanowire-semiconductor substrate. Transferring nanowires on PCL substrates is promising for implanting nanowires in-vivo with a possible reduced inflammation compared to when hard semi-conductor substrates are implanted together with the nanowires. The nanowire-PCL hybrid substrates could also be used as biocompatible cell culture substrates. Finally, using nanowires on PCL substrates would enable to recycle the expensive GaP substrate and repeatedly grow nanowires on the same substrate. (C) 2015 The Authors. Published by Elsevier B.V. (Less)
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author
organization
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Contribution to journal
publication status
published
subject
keywords
Nanowires, Polycaprolactone, Biocompatibility, Polymer, Gallium, phosphide, Cells
in
Microelectronic Engineering
volume
135
pages
52 - 56
publisher
Elsevier
external identifiers
  • wos:000353849100010
  • scopus:84925432829
ISSN
1873-5568
DOI
10.1016/j.mee.2015.03.007
language
English
LU publication?
yes
id
d0e9936b-7beb-40e4-856f-18d80fbb8a87 (old id 7439197)
date added to LUP
2015-06-24 11:30:30
date last changed
2017-10-01 03:15:42
@article{d0e9936b-7beb-40e4-856f-18d80fbb8a87,
  abstract     = {We used two methods, namely stamping and printing, to transfer arrays of epitaxial gallium phosphide (Gap) nanowires from their growth substrate to a soft, biodegradable layer of polycaprolactone (PCL). Using the stamping method resulted in a very inhomogeneous surface topography with a wide distribution of transferred nanowire lengths, whereas using the printing method resulted in an homogeneous substrate topography over several mm(2). PC12 cells were cultured on the hybrid nanowire-PCL substrates realized using the printing method and exhibited an increased attachment on these substrates, compared to the original nanowire-semiconductor substrate. Transferring nanowires on PCL substrates is promising for implanting nanowires in-vivo with a possible reduced inflammation compared to when hard semi-conductor substrates are implanted together with the nanowires. The nanowire-PCL hybrid substrates could also be used as biocompatible cell culture substrates. Finally, using nanowires on PCL substrates would enable to recycle the expensive GaP substrate and repeatedly grow nanowires on the same substrate. (C) 2015 The Authors. Published by Elsevier B.V.},
  author       = {von Ahnen, Inga and Piret, Gaelle and Prinz, Christelle},
  issn         = {1873-5568},
  keyword      = {Nanowires,Polycaprolactone,Biocompatibility,Polymer,Gallium,phosphide,Cells},
  language     = {eng},
  pages        = {52--56},
  publisher    = {Elsevier},
  series       = {Microelectronic Engineering},
  title        = {Transfer of vertical nanowire arrays on polycaprolactone substrates for biological applications},
  url          = {http://dx.doi.org/10.1016/j.mee.2015.03.007},
  volume       = {135},
  year         = {2015},
}