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In vivo magnetic resonance imaging and spectroscopy. Technological advances and opportunities for applications continue to abound

van Zijl, Peter and Knutsson, Linda LU (2019) In Journal of Magnetic Resonance 306. p.55-65
Abstract

Over the past decades, the field of in vivo magnetic resonance (MR) has built up an impressive repertoire of data acquisition and analysis technologies for anatomical, functional, physiological, and molecular imaging, the description of which requires many book volumes. As such it is impossible for a few authors to have an authoritative overview of the field and for a brief article to be inclusive. We will therefore focus mainly on data acquisition and attempt to give some insight into the principles underlying current advanced methods in the field and the potential for further innovation. In our view, the foreseeable future is expected to show continued rapid progress, for instance in imaging of microscopic tissue properties in vivo,... (More)

Over the past decades, the field of in vivo magnetic resonance (MR) has built up an impressive repertoire of data acquisition and analysis technologies for anatomical, functional, physiological, and molecular imaging, the description of which requires many book volumes. As such it is impossible for a few authors to have an authoritative overview of the field and for a brief article to be inclusive. We will therefore focus mainly on data acquisition and attempt to give some insight into the principles underlying current advanced methods in the field and the potential for further innovation. In our view, the foreseeable future is expected to show continued rapid progress, for instance in imaging of microscopic tissue properties in vivo, assessment of functional and anatomical connectivity, higher resolution physiologic and metabolic imaging, and even imaging of receptor binding. In addition, acquisition speed and information content will continue to increase due to the continuous development of approaches for parallel imaging (including simultaneous multi-slice imaging), compressed sensing, and MRI fingerprinting. Finally, artificial intelligence approaches are becoming more realistic and will have a tremendous effect on both acquisition and analysis strategies. Together, these developments will continue to provide opportunity for scientific discovery and, in combination with large data sets from other fields such as genomics, allow the ultimate realization of precision medicine in the clinic.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Magnetic Resonance
volume
306
pages
11 pages
publisher
Elsevier
external identifiers
  • pmid:31377150
  • scopus:85069944937
ISSN
1096-0856
DOI
10.1016/j.jmr.2019.07.034
language
English
LU publication?
yes
additional info
Copyright © 2019 Elsevier Inc. All rights reserved.
id
74484632-a665-4161-9690-093ea0e47820
date added to LUP
2019-08-05 16:45:24
date last changed
2020-01-28 13:16:54
@article{74484632-a665-4161-9690-093ea0e47820,
  abstract     = {<p>Over the past decades, the field of in vivo magnetic resonance (MR) has built up an impressive repertoire of data acquisition and analysis technologies for anatomical, functional, physiological, and molecular imaging, the description of which requires many book volumes. As such it is impossible for a few authors to have an authoritative overview of the field and for a brief article to be inclusive. We will therefore focus mainly on data acquisition and attempt to give some insight into the principles underlying current advanced methods in the field and the potential for further innovation. In our view, the foreseeable future is expected to show continued rapid progress, for instance in imaging of microscopic tissue properties in vivo, assessment of functional and anatomical connectivity, higher resolution physiologic and metabolic imaging, and even imaging of receptor binding. In addition, acquisition speed and information content will continue to increase due to the continuous development of approaches for parallel imaging (including simultaneous multi-slice imaging), compressed sensing, and MRI fingerprinting. Finally, artificial intelligence approaches are becoming more realistic and will have a tremendous effect on both acquisition and analysis strategies. Together, these developments will continue to provide opportunity for scientific discovery and, in combination with large data sets from other fields such as genomics, allow the ultimate realization of precision medicine in the clinic.</p>},
  author       = {van Zijl, Peter and Knutsson, Linda},
  issn         = {1096-0856},
  language     = {eng},
  pages        = {55--65},
  publisher    = {Elsevier},
  series       = {Journal of Magnetic Resonance},
  title        = {In vivo magnetic resonance imaging and spectroscopy. Technological advances and opportunities for applications continue to abound},
  url          = {http://dx.doi.org/10.1016/j.jmr.2019.07.034},
  doi          = {10.1016/j.jmr.2019.07.034},
  volume       = {306},
  year         = {2019},
}