An electrophysiologist perspective on risk stratification in heart failure: can better understanding of the condition of the cardiac sympathetic nervous system help?
(2015) In Journal of Nuclear Medicine 56(Suppl 4). p.59-64- Abstract
- Heart failure is often complicated by arrhythmias that can adversely affect the quality of life and increase the risk for sudden cardiac death. Current risk stratification strategies for sudden cardiac death in the heart failure patient are not ideal, with much potential for further refinement. Overactivation of the sympathetic nervous system has been shown to be associated with worsening heart failure as well as arrhythmic events. Recent advances in our understanding of the autonomic nervous system and new methods for quantification of the pathologic activation of the sympathetic nerves have triggered increasing interest in this field. This viewpoint focuses on the need for and challenges of risk stratification of sudden death in the... (More)
- Heart failure is often complicated by arrhythmias that can adversely affect the quality of life and increase the risk for sudden cardiac death. Current risk stratification strategies for sudden cardiac death in the heart failure patient are not ideal, with much potential for further refinement. Overactivation of the sympathetic nervous system has been shown to be associated with worsening heart failure as well as arrhythmic events. Recent advances in our understanding of the autonomic nervous system and new methods for quantification of the pathologic activation of the sympathetic nerves have triggered increasing interest in this field. This viewpoint focuses on the need for and challenges of risk stratification of sudden death in the heart failure patient and discusses the potential value of measuring sympathetic nervous system activity to better stratify risk and to select patients with heart failure for implantable cardioverter defibrillator therapy. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7508510
- author
- Borgquist, Rasmus
LU
and Singh, Jagmeet P
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Nuclear Medicine
- volume
- 56
- issue
- Suppl 4
- pages
- 59 - 64
- publisher
- Society of Nuclear Medicine
- external identifiers
-
- pmid:26033906
- wos:000355643200011
- scopus:84938873225
- pmid:26033906
- ISSN
- 0161-5505
- DOI
- 10.2967/jnumed.114.148452
- language
- English
- LU publication?
- yes
- id
- d07052ff-7034-442d-bcab-4fa0d10da935 (old id 7508510)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26033906?dopt=Abstract
- date added to LUP
- 2016-04-01 10:29:36
- date last changed
- 2022-01-25 23:48:36
@article{d07052ff-7034-442d-bcab-4fa0d10da935, abstract = {{Heart failure is often complicated by arrhythmias that can adversely affect the quality of life and increase the risk for sudden cardiac death. Current risk stratification strategies for sudden cardiac death in the heart failure patient are not ideal, with much potential for further refinement. Overactivation of the sympathetic nervous system has been shown to be associated with worsening heart failure as well as arrhythmic events. Recent advances in our understanding of the autonomic nervous system and new methods for quantification of the pathologic activation of the sympathetic nerves have triggered increasing interest in this field. This viewpoint focuses on the need for and challenges of risk stratification of sudden death in the heart failure patient and discusses the potential value of measuring sympathetic nervous system activity to better stratify risk and to select patients with heart failure for implantable cardioverter defibrillator therapy.}}, author = {{Borgquist, Rasmus and Singh, Jagmeet P}}, issn = {{0161-5505}}, language = {{eng}}, number = {{Suppl 4}}, pages = {{59--64}}, publisher = {{Society of Nuclear Medicine}}, series = {{Journal of Nuclear Medicine}}, title = {{An electrophysiologist perspective on risk stratification in heart failure: can better understanding of the condition of the cardiac sympathetic nervous system help?}}, url = {{http://dx.doi.org/10.2967/jnumed.114.148452}}, doi = {{10.2967/jnumed.114.148452}}, volume = {{56}}, year = {{2015}}, }