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Ethanol reduces rCBF activation of left dorsolateral prefrontal cortex during a verbal fluency task

Wendt, Peter E and Risberg, Jarl LU (2001) In Brain and Language 77(2). p.197-215
Abstract
Measurements of regional cerebral blood flow were made in 20 healthy young male subjects during sobriety and inebriation (0.06 % blood alcohol) during rest and during performance of a word fluency test. Word production was decreased during inebriation. The activation within the frontotemporal part of the left dorsolateral prefrontal cortex was preserved during intoxication. During inebriation no activation response to the word fluency test was seen in the anterior prefrontal part of the dorsolateral prefrontal cortex. This area showed a marked activation response during sobriety. Hemispheric function and specialization seems thus to be adversely affected by ethanol.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
DLPFC, verbal fluency, cortical asymmetry, ethanol, functional lateralization, Key Words: regional cerebral blood flow
in
Brain and Language
volume
77
issue
2
pages
197 - 215
publisher
Academic Press
external identifiers
  • scopus:0034990809
ISSN
1090-2155
DOI
10.1006/brln.2000.2434
language
English
LU publication?
yes
id
b5afce21-d149-4a8e-af54-89080a0de2eb (old id 758348)
date added to LUP
2008-01-03 16:09:33
date last changed
2018-03-25 04:15:11
@article{b5afce21-d149-4a8e-af54-89080a0de2eb,
  abstract     = {Measurements of regional cerebral blood flow were made in 20 healthy young male subjects during sobriety and inebriation (0.06 % blood alcohol) during rest and during performance of a word fluency test. Word production was decreased during inebriation. The activation within the frontotemporal part of the left dorsolateral prefrontal cortex was preserved during intoxication. During inebriation no activation response to the word fluency test was seen in the anterior prefrontal part of the dorsolateral prefrontal cortex. This area showed a marked activation response during sobriety. Hemispheric function and specialization seems thus to be adversely affected by ethanol.},
  author       = {Wendt, Peter E and Risberg, Jarl},
  issn         = {1090-2155},
  keyword      = {DLPFC,verbal fluency,cortical asymmetry,ethanol,functional lateralization,Key Words: regional cerebral blood flow},
  language     = {eng},
  number       = {2},
  pages        = {197--215},
  publisher    = {Academic Press},
  series       = {Brain and Language},
  title        = {Ethanol reduces rCBF activation of left dorsolateral prefrontal cortex during a verbal fluency task},
  url          = {http://dx.doi.org/10.1006/brln.2000.2434},
  volume       = {77},
  year         = {2001},
}