Measuring density and compressibility of white blood cells and prostate cancer cells by microchannel acoustophoresis
(2011) 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 1. p.127-129- Abstract
We present a novel method for the determination of density and compressibility of individual particles and cells undergoing microchannel acoustophoresis in an arbitrary 2D acoustic field. Our method is a critical advancement within acoustophoretic separation of biological cells, as the ability to determine the density and compressibility of individual cells enables the prediction and alteration of the separation outcome for a given cell mixture. We apply the method on white blood cells (WBCs) and DU145 prostate cancer cells (DUCs) aiming to improve isolation of circulating tumor cells from blood, an emerging tool in the monitoring and characterizing of metastatic cancer.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/75991afd-683f-40c8-aca5-274cc478bbde
- author
- Barnkob, Rune ; Augustsson, Per LU ; Magnusson, Cecilia LU ; Lilja, Hans LU ; Laurell, Thomas LU and Bruus, Henrik
- organization
- publishing date
- 2011
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Acoustophoresis, Cell handling, Micro-PIV, Ultrasound resonances
- host publication
- 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
- series title
- 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
- volume
- 1
- pages
- 127 - 129
- conference name
- 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
- conference location
- Seattle, WA, United States
- conference dates
- 2011-10-02 - 2011-10-06
- external identifiers
-
- scopus:84878143928
- ISBN
- 9781618395955
- language
- English
- LU publication?
- yes
- id
- 75991afd-683f-40c8-aca5-274cc478bbde
- date added to LUP
- 2023-02-10 11:16:46
- date last changed
- 2023-03-06 15:38:14
@inproceedings{75991afd-683f-40c8-aca5-274cc478bbde, abstract = {{<p>We present a novel method for the determination of density and compressibility of individual particles and cells undergoing microchannel acoustophoresis in an arbitrary 2D acoustic field. Our method is a critical advancement within acoustophoretic separation of biological cells, as the ability to determine the density and compressibility of individual cells enables the prediction and alteration of the separation outcome for a given cell mixture. We apply the method on white blood cells (WBCs) and DU145 prostate cancer cells (DUCs) aiming to improve isolation of circulating tumor cells from blood, an emerging tool in the monitoring and characterizing of metastatic cancer.</p>}}, author = {{Barnkob, Rune and Augustsson, Per and Magnusson, Cecilia and Lilja, Hans and Laurell, Thomas and Bruus, Henrik}}, booktitle = {{15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011}}, isbn = {{9781618395955}}, keywords = {{Acoustophoresis; Cell handling; Micro-PIV; Ultrasound resonances}}, language = {{eng}}, pages = {{127--129}}, series = {{15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011}}, title = {{Measuring density and compressibility of white blood cells and prostate cancer cells by microchannel acoustophoresis}}, volume = {{1}}, year = {{2011}}, }