Advanced

Cancer and Risk of COVID-19 Through a General Community Survey

Lee, Karla A. ; Ma, Wenjie ; Sikavi, Daniel R. ; Drew, David A. ; Nguyen, Long H. ; Bowyer, Ruth C.E. ; Cardoso, M. Jorge ; Fall, Tove LU ; Freidin, Maxim B. and Gomez, Maria LU , et al. (2021) In Oncologist 26(1).
Abstract

Individuals with cancer may be at high risk for coronavirus disease 2019 (COVID-19) and adverse outcomes. However, evidence from large population-based studies examining whether cancer and cancer-related therapy exacerbates the risk of COVID-19 infection is still limited. Data were collected from the COVID Symptom Study smartphone application since March 29 through May 8, 2020. Among 23,266 participants with cancer and 1,784,293 without cancer, we documented 10,404 reports of a positive COVID-19 test. Compared with participants without cancer, those living with cancer had a 60% increased risk of a positive COVID-19 test. Among patients with cancer, current treatment with chemotherapy or immunotherapy was associated with a 2.2-fold... (More)

Individuals with cancer may be at high risk for coronavirus disease 2019 (COVID-19) and adverse outcomes. However, evidence from large population-based studies examining whether cancer and cancer-related therapy exacerbates the risk of COVID-19 infection is still limited. Data were collected from the COVID Symptom Study smartphone application since March 29 through May 8, 2020. Among 23,266 participants with cancer and 1,784,293 without cancer, we documented 10,404 reports of a positive COVID-19 test. Compared with participants without cancer, those living with cancer had a 60% increased risk of a positive COVID-19 test. Among patients with cancer, current treatment with chemotherapy or immunotherapy was associated with a 2.2-fold increased risk of a positive test. The association between cancer and COVID-19 infection was stronger among participants >65 years and males. Future studies are needed to identify subgroups by tumor types and treatment regimens who are particularly at risk for COVID-19 infection and adverse outcomes.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Covid-19, SARS-CoV-2
in
Oncologist
volume
26
issue
1
publisher
AlphaMed Press
external identifiers
  • scopus:85090316468
  • pmid:32845538
ISSN
1083-7159
DOI
10.1634/theoncologist.2020-0572
project
COVID Symptom Study Sweden
language
English
LU publication?
yes
id
75a74cbf-6ebf-4e1f-8e6c-7a44a482e278
date added to LUP
2020-10-23 15:51:33
date last changed
2021-05-05 01:56:32
@article{75a74cbf-6ebf-4e1f-8e6c-7a44a482e278,
  abstract     = {<p>Individuals with cancer may be at high risk for coronavirus disease 2019 (COVID-19) and adverse outcomes. However, evidence from large population-based studies examining whether cancer and cancer-related therapy exacerbates the risk of COVID-19 infection is still limited. Data were collected from the COVID Symptom Study smartphone application since March 29 through May 8, 2020. Among 23,266 participants with cancer and 1,784,293 without cancer, we documented 10,404 reports of a positive COVID-19 test. Compared with participants without cancer, those living with cancer had a 60% increased risk of a positive COVID-19 test. Among patients with cancer, current treatment with chemotherapy or immunotherapy was associated with a 2.2-fold increased risk of a positive test. The association between cancer and COVID-19 infection was stronger among participants &gt;65 years and males. Future studies are needed to identify subgroups by tumor types and treatment regimens who are particularly at risk for COVID-19 infection and adverse outcomes.</p>},
  author       = {Lee, Karla A. and Ma, Wenjie and Sikavi, Daniel R. and Drew, David A. and Nguyen, Long H. and Bowyer, Ruth C.E. and Cardoso, M. Jorge and Fall, Tove and Freidin, Maxim B. and Gomez, Maria and Graham, Mark and Guo, Chuan Guo and Joshi, Amit D. and Kwon, Sohee and Lo, Chun Han and Lochlainn, Mary Ni and Menni, Cristina and Murray, Benjamin and Mehta, Raaj and Song, Mingyang and Sudre, Carole H. and Bataille, Veronique and Varsavsky, Thomas and Visconti, Alessia and Franks, Paul W. and Wolf, Jonathan and Steves, Claire J. and Ourselin, Sebastien and Spector, Tim D. and Chan, Andrew T.},
  issn         = {1083-7159},
  language     = {eng},
  number       = {1},
  publisher    = {AlphaMed Press},
  series       = {Oncologist},
  title        = {Cancer and Risk of COVID-19 Through a General Community Survey},
  url          = {http://dx.doi.org/10.1634/theoncologist.2020-0572},
  doi          = {10.1634/theoncologist.2020-0572},
  volume       = {26},
  year         = {2021},
}