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Non-fibrosing sclerosing epithelioid fibrosarcoma: An unusual variant.

Puls, Florian ; Magnusson, Linda LU ; Niblett, Angela ; Douis, Hassan ; Peake, David ; Taniere, Philippe ; Kindblom, Lars-Gunnar and Mertens, Fredrik LU (2015) In Histopathology
Abstract
Sclerosing epithelioid fibrosarcoma (SEF), first described in 1995, is a rare aggressive sarcoma morphologically defined by "epithelioid fibroblasts arranged in distinct cords and nests in a densely sclerotic, hyalinised stroma". SEF can mimic metastatic carcinoma within desmoplastic stroma, lymphoma and other mesenchymal neoplasms such as myoepithelioma, making it difficult to diagnose. In a subset of cases there is morphological overlap between SEF and low grade fibromyxoid sarcoma (LGFMS), a low grade fibroblastic sarcoma. Progression of LGFMS to SEF in single cases is well documented. Recent studies detected EWSR1-CREB3L1 fusion transcripts in a high proportion of SEF. This article is protected by copyright. All rights reserved.
Please use this url to cite or link to this publication:
author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Histopathology
publisher
Wiley-Blackwell
external identifiers
  • pmid:26212576
  • scopus:84941585705
  • wos:000372927600019
  • pmid:26212576
ISSN
0309-0167
DOI
10.1111/his.12791
language
English
LU publication?
yes
id
afb6da13-ac5b-4c98-ba6d-f1c79ff7a3c3 (old id 7720684)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26212576?dopt=Abstract
date added to LUP
2016-04-04 08:22:13
date last changed
2022-02-20 21:39:54
@article{afb6da13-ac5b-4c98-ba6d-f1c79ff7a3c3,
  abstract     = {{Sclerosing epithelioid fibrosarcoma (SEF), first described in 1995, is a rare aggressive sarcoma morphologically defined by "epithelioid fibroblasts arranged in distinct cords and nests in a densely sclerotic, hyalinised stroma". SEF can mimic metastatic carcinoma within desmoplastic stroma, lymphoma and other mesenchymal neoplasms such as myoepithelioma, making it difficult to diagnose. In a subset of cases there is morphological overlap between SEF and low grade fibromyxoid sarcoma (LGFMS), a low grade fibroblastic sarcoma. Progression of LGFMS to SEF in single cases is well documented. Recent studies detected EWSR1-CREB3L1 fusion transcripts in a high proportion of SEF. This article is protected by copyright. All rights reserved.}},
  author       = {{Puls, Florian and Magnusson, Linda and Niblett, Angela and Douis, Hassan and Peake, David and Taniere, Philippe and Kindblom, Lars-Gunnar and Mertens, Fredrik}},
  issn         = {{0309-0167}},
  language     = {{eng}},
  month        = {{07}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Histopathology}},
  title        = {{Non-fibrosing sclerosing epithelioid fibrosarcoma: An unusual variant.}},
  url          = {{http://dx.doi.org/10.1111/his.12791}},
  doi          = {{10.1111/his.12791}},
  year         = {{2015}},
}