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Non-fibrosing sclerosing epithelioid fibrosarcoma: An unusual variant.

Puls, Florian; Magnusson, Linda LU ; Niblett, Angela; Douis, Hassan; Peake, David; Taniere, Philippe; Kindblom, Lars-Gunnar and Mertens, Fredrik LU (2015) In Histopathology
Abstract
Sclerosing epithelioid fibrosarcoma (SEF), first described in 1995, is a rare aggressive sarcoma morphologically defined by "epithelioid fibroblasts arranged in distinct cords and nests in a densely sclerotic, hyalinised stroma". SEF can mimic metastatic carcinoma within desmoplastic stroma, lymphoma and other mesenchymal neoplasms such as myoepithelioma, making it difficult to diagnose. In a subset of cases there is morphological overlap between SEF and low grade fibromyxoid sarcoma (LGFMS), a low grade fibroblastic sarcoma. Progression of LGFMS to SEF in single cases is well documented. Recent studies detected EWSR1-CREB3L1 fusion transcripts in a high proportion of SEF. This article is protected by copyright. All rights reserved.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Histopathology
publisher
Wiley-Blackwell
external identifiers
  • pmid:26212576
  • scopus:84941585705
  • wos:000372927600019
ISSN
0309-0167
DOI
10.1111/his.12791
language
English
LU publication?
yes
id
afb6da13-ac5b-4c98-ba6d-f1c79ff7a3c3 (old id 7720684)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26212576?dopt=Abstract
date added to LUP
2015-08-10 17:24:56
date last changed
2017-01-01 07:36:26
@article{afb6da13-ac5b-4c98-ba6d-f1c79ff7a3c3,
  abstract     = {Sclerosing epithelioid fibrosarcoma (SEF), first described in 1995, is a rare aggressive sarcoma morphologically defined by "epithelioid fibroblasts arranged in distinct cords and nests in a densely sclerotic, hyalinised stroma". SEF can mimic metastatic carcinoma within desmoplastic stroma, lymphoma and other mesenchymal neoplasms such as myoepithelioma, making it difficult to diagnose. In a subset of cases there is morphological overlap between SEF and low grade fibromyxoid sarcoma (LGFMS), a low grade fibroblastic sarcoma. Progression of LGFMS to SEF in single cases is well documented. Recent studies detected EWSR1-CREB3L1 fusion transcripts in a high proportion of SEF. This article is protected by copyright. All rights reserved.},
  author       = {Puls, Florian and Magnusson, Linda and Niblett, Angela and Douis, Hassan and Peake, David and Taniere, Philippe and Kindblom, Lars-Gunnar and Mertens, Fredrik},
  issn         = {0309-0167},
  language     = {eng},
  month        = {07},
  publisher    = {Wiley-Blackwell},
  series       = {Histopathology},
  title        = {Non-fibrosing sclerosing epithelioid fibrosarcoma: An unusual variant.},
  url          = {http://dx.doi.org/10.1111/his.12791},
  year         = {2015},
}