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Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia

Andersson, Maria ; Bergendorff, Ola LU ; Nielsen, Mogens ; Sterner, Olov LU ; Witt, Robin ; Ai, Jinglu ; Lu, Aiping and Wang, An Min (1995) In Phytochemistry 38(4). p.835-836
Abstract
S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.
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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Phytochemistry
volume
38
issue
4
pages
835 - 836
publisher
Elsevier
external identifiers
  • pmid:7766386
  • scopus:0029257197
ISSN
0031-9422
DOI
10.1016/0031-9422(94)00771-K
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)
id
77582624-c154-4150-a110-8375a14145b4 (old id 1109354)
date added to LUP
2016-04-01 15:45:22
date last changed
2021-08-08 05:14:19
@article{77582624-c154-4150-a110-8375a14145b4,
  abstract     = {{S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.}},
  author       = {{Andersson, Maria and Bergendorff, Ola and Nielsen, Mogens and Sterner, Olov and Witt, Robin and Ai, Jinglu and Lu, Aiping and Wang, An Min}},
  issn         = {{0031-9422}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{835--836}},
  publisher    = {{Elsevier}},
  series       = {{Phytochemistry}},
  title        = {{Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia}},
  url          = {{http://dx.doi.org/10.1016/0031-9422(94)00771-K}},
  doi          = {{10.1016/0031-9422(94)00771-K}},
  volume       = {{38}},
  year         = {{1995}},
}