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Atrial fibrillatory rate and irregularity of ventricular response as predictors of clinical outcome in patients with atrial fibrillation

Platonov, Pyotr LU and Holmqvist, Fredrik LU (2011) Conference of the International-Society-for-Computerized-Electrocardiology 44(6). p.673-677
Abstract
Atrial fibrillation (AF) remains the most common arrhythmia encountered in clinical practice. Electrocardiogram (ECG)-based predictors of clinical outcome, however, have mostly been studied during sinus rhythm, whereas noninvasive risk stratification of patients with AF remains largely unexplored. Advances in ECG signal processing have led to the development of noninvasive methods of atrial fibrillatory rate (AFR) assessment using spatiotemporal QRST cancellation and time frequency analysis that demonstrated its predictive value for the outcome of pharmacologic and catheter-based interventions for AF. Recently, the prognostic value of AFR was evaluated in patients with congestive heart failure and indicated that reduced AFR may be an... (More)
Atrial fibrillation (AF) remains the most common arrhythmia encountered in clinical practice. Electrocardiogram (ECG)-based predictors of clinical outcome, however, have mostly been studied during sinus rhythm, whereas noninvasive risk stratification of patients with AF remains largely unexplored. Advances in ECG signal processing have led to the development of noninvasive methods of atrial fibrillatory rate (AFR) assessment using spatiotemporal QRST cancellation and time frequency analysis that demonstrated its predictive value for the outcome of pharmacologic and catheter-based interventions for AF. Recently, the prognostic value of AFR was evaluated in patients with congestive heart failure and indicated that reduced AFR may be an independent predictor of total and congestive heart failure-related mortality. A high degree of irregularity of the RR intervals during AF and its dependence on the modulation of the atrioventricular conduction rather than sinus node automaticity hampers the use of conventional heart rate variability approach in patients with AF. However, RR irregularity measures that can be applied to short-time ECG recordings appear to be promising predictors of clinical outcome. (C) 2011 Elsevier Inc. All rights reserved. (Less)
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Atrial fibrillation, Atrial fibrillatory rate, Ventricular response, Heart rate variability, Risk stratification
host publication
Journal of Electrocardiology
volume
44
issue
6
pages
673 - 677
publisher
Elsevier
conference name
Conference of the International-Society-for-Computerized-Electrocardiology
conference dates
2011-04-13 - 2011-04-17
external identifiers
  • wos:000296660500013
  • scopus:80054908962
  • pmid:21907998
ISSN
1532-8430
0022-0736
DOI
10.1016/j.jelectrocard.2011.07.024
language
English
LU publication?
yes
id
7773481c-f379-451b-8cd0-602bdc2b607c (old id 2253219)
date added to LUP
2016-04-01 11:07:00
date last changed
2025-01-01 05:28:42
@inproceedings{7773481c-f379-451b-8cd0-602bdc2b607c,
  abstract     = {{Atrial fibrillation (AF) remains the most common arrhythmia encountered in clinical practice. Electrocardiogram (ECG)-based predictors of clinical outcome, however, have mostly been studied during sinus rhythm, whereas noninvasive risk stratification of patients with AF remains largely unexplored. Advances in ECG signal processing have led to the development of noninvasive methods of atrial fibrillatory rate (AFR) assessment using spatiotemporal QRST cancellation and time frequency analysis that demonstrated its predictive value for the outcome of pharmacologic and catheter-based interventions for AF. Recently, the prognostic value of AFR was evaluated in patients with congestive heart failure and indicated that reduced AFR may be an independent predictor of total and congestive heart failure-related mortality. A high degree of irregularity of the RR intervals during AF and its dependence on the modulation of the atrioventricular conduction rather than sinus node automaticity hampers the use of conventional heart rate variability approach in patients with AF. However, RR irregularity measures that can be applied to short-time ECG recordings appear to be promising predictors of clinical outcome. (C) 2011 Elsevier Inc. All rights reserved.}},
  author       = {{Platonov, Pyotr and Holmqvist, Fredrik}},
  booktitle    = {{Journal of Electrocardiology}},
  issn         = {{1532-8430}},
  keywords     = {{Atrial fibrillation; Atrial fibrillatory rate; Ventricular response; Heart rate variability; Risk stratification}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{673--677}},
  publisher    = {{Elsevier}},
  title        = {{Atrial fibrillatory rate and irregularity of ventricular response as predictors of clinical outcome in patients with atrial fibrillation}},
  url          = {{http://dx.doi.org/10.1016/j.jelectrocard.2011.07.024}},
  doi          = {{10.1016/j.jelectrocard.2011.07.024}},
  volume       = {{44}},
  year         = {{2011}},
}