Evaluation Of Handheld Point-of-Care-Ultrasound (POCUS) in Screening for Abdominal Aortic Aneurysm in Men : A Comparative, Cohort Study
(2025) In Ultrasound in Medicine and Biology 51(10). p.1840-1845- Abstract
OBJECTIVE: Screening for abdominal aortic aneurysm (AAA) using ultrasound in men reduces aneurysm-related mortality. Ambulatory screening and surveillance procedures facilitated by point-of-care ultrasound (POCUS) may improve adherence to screening programs. This proof-of-concept study evaluated whether infrarenal aortic diameter (IAD) can be accurately and interchangeably measured using handheld POCUS-an ultrasound probe connected to a tablet-compared to standard cart-based ultrasound equipment.
METHODS: This comparative cohort study included men with an IAD of 25-29 mm during AAA screening and re-examined them after 5-12 years, anticipating most would approach the 30 mm AAA threshold. Three IAD measurements were taken using both... (More)
OBJECTIVE: Screening for abdominal aortic aneurysm (AAA) using ultrasound in men reduces aneurysm-related mortality. Ambulatory screening and surveillance procedures facilitated by point-of-care ultrasound (POCUS) may improve adherence to screening programs. This proof-of-concept study evaluated whether infrarenal aortic diameter (IAD) can be accurately and interchangeably measured using handheld POCUS-an ultrasound probe connected to a tablet-compared to standard cart-based ultrasound equipment.
METHODS: This comparative cohort study included men with an IAD of 25-29 mm during AAA screening and re-examined them after 5-12 years, anticipating most would approach the 30 mm AAA threshold. Three IAD measurements were taken using both POCUS (Lumify™, Philips) and standard US (LOGIQ™ 9E, GE). Bias, limits of agreement between devices and repeatability within devices were evaluated. Sensitivity and specificity of POCUS for AAA detection (IAD ≥30 mm) compared to standard ultrasound were also assessed.
RESULTS: In total, 230 men participated. The median age was 75.0 years (IQR: 72.9-76.5), BMI 27.7 (26.0-30.5), and IAD 27.1 mm (23.7-32.8) respectively. POCUS underestimated IAD by 0.3 mm compared to standard US, with 95% limits of agreement ±3.0 mm. Repeatability was ±2.5 mm for standard ultrasound and ±3.2 mm for POCUS. The sensitivity and specificity of POCUS for AAA diagnosis, compared to standard ultrasound, are 94% and 98%, respectively.
CONCLUSION: POCUS showed no systematic bias of clinical importance in measuring IAD although with a slightly wider repeatability interval compared to standard US implying the possibility to consider POCUS devices for AAA-screening purposes.
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- author
- Starck, Joachim LU ; Brunkwall, Silke ; Gottsäter, Anders LU and Holst, Jan LU
- organization
- publishing date
- 2025-10
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Humans, Aortic Aneurysm, Abdominal/diagnostic imaging, Male, Aged, Ultrasonography/methods, Point-of-Care Systems, Sensitivity and Specificity, Cohort Studies, Reproducibility of Results, Mass Screening/methods, Aorta, Abdominal/diagnostic imaging
- in
- Ultrasound in Medicine and Biology
- volume
- 51
- issue
- 10
- pages
- 1840 - 1845
- publisher
- Elsevier
- external identifiers
-
- scopus:105012093663
- pmid:40738797
- ISSN
- 0301-5629
- DOI
- 10.1016/j.ultrasmedbio.2025.07.004
- language
- English
- LU publication?
- yes
- additional info
- Copyright © 2025 The Authors. Published by Elsevier Inc. All rights reserved.
- id
- 7776ff14-fba8-4ab5-8861-a23bcb2bf31f
- date added to LUP
- 2025-10-11 16:32:59
- date last changed
- 2025-10-14 11:58:09
@article{7776ff14-fba8-4ab5-8861-a23bcb2bf31f, abstract = {{<p>OBJECTIVE: Screening for abdominal aortic aneurysm (AAA) using ultrasound in men reduces aneurysm-related mortality. Ambulatory screening and surveillance procedures facilitated by point-of-care ultrasound (POCUS) may improve adherence to screening programs. This proof-of-concept study evaluated whether infrarenal aortic diameter (IAD) can be accurately and interchangeably measured using handheld POCUS-an ultrasound probe connected to a tablet-compared to standard cart-based ultrasound equipment.</p><p>METHODS: This comparative cohort study included men with an IAD of 25-29 mm during AAA screening and re-examined them after 5-12 years, anticipating most would approach the 30 mm AAA threshold. Three IAD measurements were taken using both POCUS (Lumify™, Philips) and standard US (LOGIQ™ 9E, GE). Bias, limits of agreement between devices and repeatability within devices were evaluated. Sensitivity and specificity of POCUS for AAA detection (IAD ≥30 mm) compared to standard ultrasound were also assessed.</p><p>RESULTS: In total, 230 men participated. The median age was 75.0 years (IQR: 72.9-76.5), BMI 27.7 (26.0-30.5), and IAD 27.1 mm (23.7-32.8) respectively. POCUS underestimated IAD by 0.3 mm compared to standard US, with 95% limits of agreement ±3.0 mm. Repeatability was ±2.5 mm for standard ultrasound and ±3.2 mm for POCUS. The sensitivity and specificity of POCUS for AAA diagnosis, compared to standard ultrasound, are 94% and 98%, respectively.</p><p>CONCLUSION: POCUS showed no systematic bias of clinical importance in measuring IAD although with a slightly wider repeatability interval compared to standard US implying the possibility to consider POCUS devices for AAA-screening purposes.</p>}}, author = {{Starck, Joachim and Brunkwall, Silke and Gottsäter, Anders and Holst, Jan}}, issn = {{0301-5629}}, keywords = {{Humans; Aortic Aneurysm, Abdominal/diagnostic imaging; Male; Aged; Ultrasonography/methods; Point-of-Care Systems; Sensitivity and Specificity; Cohort Studies; Reproducibility of Results; Mass Screening/methods; Aorta, Abdominal/diagnostic imaging}}, language = {{eng}}, number = {{10}}, pages = {{1840--1845}}, publisher = {{Elsevier}}, series = {{Ultrasound in Medicine and Biology}}, title = {{Evaluation Of Handheld Point-of-Care-Ultrasound (POCUS) in Screening for Abdominal Aortic Aneurysm in Men : A Comparative, Cohort Study}}, url = {{http://dx.doi.org/10.1016/j.ultrasmedbio.2025.07.004}}, doi = {{10.1016/j.ultrasmedbio.2025.07.004}}, volume = {{51}}, year = {{2025}}, }