Changes in the pattern of paracetamol use in the periconception period in a Danish cohort
(2015) In Acta Obstetricia et Gynecologica Scandinavica 94(8). p.898-903- Abstract
- Paracetamol is the most commonly used over-the-counter drug in pregnancy. It is generally considered to be safe, but prolonged antenatal exposure has been associated with offspring short- and long-term morbidity. Our aim was to describe the pattern of paracetamol use with a focus on frequent ingestion (more than once a week), 3months before and in early pregnancy. In this cohort, 8650 pregnant women responded to a web-based clinical questionnaire that included questions about drug use. Paracetamol was the most used drug before and in early pregnancy (35.2% and 6.5% of respondents, respectively). The proportion of frequent users decreased from 3.9% before to 0.9% in early pregnancy. Frequent paracetamol use was associated with smoking,... (More)
- Paracetamol is the most commonly used over-the-counter drug in pregnancy. It is generally considered to be safe, but prolonged antenatal exposure has been associated with offspring short- and long-term morbidity. Our aim was to describe the pattern of paracetamol use with a focus on frequent ingestion (more than once a week), 3months before and in early pregnancy. In this cohort, 8650 pregnant women responded to a web-based clinical questionnaire that included questions about drug use. Paracetamol was the most used drug before and in early pregnancy (35.2% and 6.5% of respondents, respectively). The proportion of frequent users decreased from 3.9% before to 0.9% in early pregnancy. Frequent paracetamol use was associated with smoking, co-morbidities, body mass index 25kg/m(2), unplanned pregnancy, no education and inability to understand Danish. A significant decrease in the proportion of women with any paracetamol use in early pregnancy was noted after access to large packs was restricted by legislation. (Less)
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https://lup.lub.lu.se/record/7779716
- author
- Ersboll, Anne S. ; Hedegaard, Mette ; Damm, Peter ; Johansen, Marianne ; Tabor, Ann and Hegaard, Hanne Kristine LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Paracetamol, acetaminophen, pregnancy, antenatal care, prenatal care, exposure
- in
- Acta Obstetricia et Gynecologica Scandinavica
- volume
- 94
- issue
- 8
- pages
- 898 - 903
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000357983900013
- scopus:84937073553
- pmid:25939806
- ISSN
- 1600-0412
- DOI
- 10.1111/aogs.12667
- project
- Children with cancer
- language
- English
- LU publication?
- yes
- id
- 0fac7934-5e39-423c-8d77-731ec4f1ca4c (old id 7779716)
- date added to LUP
- 2016-04-01 14:00:52
- date last changed
- 2022-01-27 22:22:31
@article{0fac7934-5e39-423c-8d77-731ec4f1ca4c,
abstract = {{Paracetamol is the most commonly used over-the-counter drug in pregnancy. It is generally considered to be safe, but prolonged antenatal exposure has been associated with offspring short- and long-term morbidity. Our aim was to describe the pattern of paracetamol use with a focus on frequent ingestion (more than once a week), 3months before and in early pregnancy. In this cohort, 8650 pregnant women responded to a web-based clinical questionnaire that included questions about drug use. Paracetamol was the most used drug before and in early pregnancy (35.2% and 6.5% of respondents, respectively). The proportion of frequent users decreased from 3.9% before to 0.9% in early pregnancy. Frequent paracetamol use was associated with smoking, co-morbidities, body mass index 25kg/m(2), unplanned pregnancy, no education and inability to understand Danish. A significant decrease in the proportion of women with any paracetamol use in early pregnancy was noted after access to large packs was restricted by legislation.}},
author = {{Ersboll, Anne S. and Hedegaard, Mette and Damm, Peter and Johansen, Marianne and Tabor, Ann and Hegaard, Hanne Kristine}},
issn = {{1600-0412}},
keywords = {{Paracetamol; acetaminophen; pregnancy; antenatal care; prenatal care; exposure}},
language = {{eng}},
number = {{8}},
pages = {{898--903}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Obstetricia et Gynecologica Scandinavica}},
title = {{Changes in the pattern of paracetamol use in the periconception period in a Danish cohort}},
url = {{http://dx.doi.org/10.1111/aogs.12667}},
doi = {{10.1111/aogs.12667}},
volume = {{94}},
year = {{2015}},
}