Contemporary approaches for imaging skeletal metastasis.
(2015) In Bone Research 3. p.15024-15024- Abstract
- The skeleton is a common site of cancer metastasis. Notably high incidences of bone lesions are found for breast, prostate, and renal carcinoma. Malignant bone tumors result in significant patient morbidity. Identification of these lesions is a critical step to accurately stratify patients, guide treatment course, monitor disease progression, and evaluate response to therapy. Diagnosis of cancer in the skeleton typically relies on indirect bone-targeted radiotracer uptake at sites of active bone remodeling. In this manuscript, we discuss established and emerging tools and techniques for detection of bone lesions, quantification of skeletal tumor burden, and current clinical challenges.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7841079
- author
- Ulmert, David LU ; Solnes, Lilja and Thorek, Daniel Lj
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Bone Research
- volume
- 3
- pages
- 15024 - 15024
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:26273541
- wos:000367643700001
- pmid:26273541
- scopus:84969976124
- ISSN
- 2095-4700
- DOI
- 10.1038/boneres.2015.24
- language
- English
- LU publication?
- yes
- id
- 8f842636-b2e4-4d1b-a400-174eb6554f60 (old id 7841079)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26273541?dopt=Abstract
- date added to LUP
- 2016-04-01 13:32:01
- date last changed
- 2022-09-26 06:53:19
@article{8f842636-b2e4-4d1b-a400-174eb6554f60, abstract = {{The skeleton is a common site of cancer metastasis. Notably high incidences of bone lesions are found for breast, prostate, and renal carcinoma. Malignant bone tumors result in significant patient morbidity. Identification of these lesions is a critical step to accurately stratify patients, guide treatment course, monitor disease progression, and evaluate response to therapy. Diagnosis of cancer in the skeleton typically relies on indirect bone-targeted radiotracer uptake at sites of active bone remodeling. In this manuscript, we discuss established and emerging tools and techniques for detection of bone lesions, quantification of skeletal tumor burden, and current clinical challenges.}}, author = {{Ulmert, David and Solnes, Lilja and Thorek, Daniel Lj}}, issn = {{2095-4700}}, language = {{eng}}, pages = {{15024--15024}}, publisher = {{Nature Publishing Group}}, series = {{Bone Research}}, title = {{Contemporary approaches for imaging skeletal metastasis.}}, url = {{https://lup.lub.lu.se/search/files/3432703/8619260.pdf}}, doi = {{10.1038/boneres.2015.24}}, volume = {{3}}, year = {{2015}}, }