Orthostatic Hypotension: Epidemiology, Prognosis, and Treatment.
Ricci, Fabrizio ; De Caterina, Raffaele and Fedorowski, Artur LU
(2015)
In Journal of the American College of Cardiology
66(7).
p.848-860
- Abstract
- Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/diastolic blood pressure decrease of at least 20/10 mm Hg upon standing. Its prevalence is age dependent, ranging from 5% in patients <50 years of age to 30% in those >70 years of age. OH may complicate treatment of hypertension, heart failure, and coronary heart disease; cause disabling symptoms, faints, and traumatic injuries; and substantially reduce quality of life. Despite being largely asymptomatic or with minimal symptoms, the presence of OH independently increases mortality and the incidence of myocardial... (More)
- Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/diastolic blood pressure decrease of at least 20/10 mm Hg upon standing. Its prevalence is age dependent, ranging from 5% in patients <50 years of age to 30% in those >70 years of age. OH may complicate treatment of hypertension, heart failure, and coronary heart disease; cause disabling symptoms, faints, and traumatic injuries; and substantially reduce quality of life. Despite being largely asymptomatic or with minimal symptoms, the presence of OH independently increases mortality and the incidence of myocardial infarction, stroke, heart failure, and atrial fibrillation. In this review, we outline the etiology and prevalence of OH in the general population, summarize its relationship with morbidity and mortality, propose a diagnostic and therapeutic algorithm, and delineate current challenges and future perspectives. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7841202
- author
- Ricci, Fabrizio
; De Caterina, Raffaele
and Fedorowski, Artur
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of the American College of Cardiology
- volume
- 66
- issue
- 7
- pages
- 848 - 860
- publisher
- Elsevier
- external identifiers
-
- wos:000359952900012
- pmid:26271068
- scopus:84939546831
- pmid:26271068
- ISSN
- 0735-1097
- DOI
- 10.1016/j.jacc.2015.06.1084
- language
- English
- LU publication?
- yes
- id
- 786c83bb-c79d-4066-a8b6-5d4924111e6e (old id 7841202)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26271068?dopt=Abstract
- date added to LUP
- 2016-04-01 10:10:38
- date last changed
- 2022-04-27 19:10:12
@article{786c83bb-c79d-4066-a8b6-5d4924111e6e,
abstract = {{Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/diastolic blood pressure decrease of at least 20/10 mm Hg upon standing. Its prevalence is age dependent, ranging from 5% in patients <50 years of age to 30% in those >70 years of age. OH may complicate treatment of hypertension, heart failure, and coronary heart disease; cause disabling symptoms, faints, and traumatic injuries; and substantially reduce quality of life. Despite being largely asymptomatic or with minimal symptoms, the presence of OH independently increases mortality and the incidence of myocardial infarction, stroke, heart failure, and atrial fibrillation. In this review, we outline the etiology and prevalence of OH in the general population, summarize its relationship with morbidity and mortality, propose a diagnostic and therapeutic algorithm, and delineate current challenges and future perspectives.}},
author = {{Ricci, Fabrizio and De Caterina, Raffaele and Fedorowski, Artur}},
issn = {{0735-1097}},
language = {{eng}},
number = {{7}},
pages = {{848--860}},
publisher = {{Elsevier}},
series = {{Journal of the American College of Cardiology}},
title = {{Orthostatic Hypotension: Epidemiology, Prognosis, and Treatment.}},
url = {{http://dx.doi.org/10.1016/j.jacc.2015.06.1084}},
doi = {{10.1016/j.jacc.2015.06.1084}},
volume = {{66}},
year = {{2015}},
}