Advanced

Molecular cloning of a small prostate protein, known as beta-microsemenoprotein, PSP94 or beta-inhibin, and demonstration of transcripts in non-genital tissues

Ulvsbäck, M. ; Lindstrom, C. ; Weiber, Håkan LU ; Abrahamsson, Per-Anders LU ; Lilja, Hans LU and Lundwall, Åke LU (1989) In Biochem Biophys Res Commun 164(3). p.5-1310
Abstract
In order to study the gene expression of the seminal plasma protein beta-microseminoprotein, also known as PSP94 and beta-inhibin, clones encoding this protein were isolated from a cDNA library constructed in lambda gt11. Nucleotide sequencing confirmed the structure of a previously cloned cDNA. By northern blot analysis identical sized transcripts were demonstrated in the prostate, the respiratory (tracheal, bronchial and lung) tissues and the antrum part of the gastric mucosa. Thus, the protein is not primarily associated with male reproductive function. Although probably of no physiological significance, a slight structural similarity to the ovarian inhibin beta-chains was identified in the C-terminal half of the molecule.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Prostate/*metabolism, Peptides/*genetics, Organ Specificity, Oligonucleotide Probes/chemical synthesis, Molecular Sequence Data, Male, Inhibins/genetics, Humans, Gene Library, DNA/*genetics, Comparative Study, Molecular, *Cloning, Northern, Blotting, Amino Acid Sequence, Base Sequence, *Prostatic Secretory Proteins, Proteins/*genetics, Research Support, Non-U.S. Gov't, Seminal Plasma Proteins, Sequence Homology, Nucleic Acid, *Transcription, Genetic
in
Biochem Biophys Res Commun
volume
164
issue
3
pages
5 - 1310
publisher
Elsevier
external identifiers
  • scopus:0024426040
language
English
LU publication?
yes
additional info
3 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Clinical Chemistry, Malmö (013016000), Surgery Research Unit (013242220), Emergency medicine/Medicine/Surgery (013240200), Department of Translational Medicine (013017500)
id
796967b0-687c-402e-b485-c6938d5024b7 (old id 3965190)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2590204
date added to LUP
2016-04-04 13:05:56
date last changed
2020-01-12 21:40:02
@article{796967b0-687c-402e-b485-c6938d5024b7,
  abstract     = {In order to study the gene expression of the seminal plasma protein beta-microseminoprotein, also known as PSP94 and beta-inhibin, clones encoding this protein were isolated from a cDNA library constructed in lambda gt11. Nucleotide sequencing confirmed the structure of a previously cloned cDNA. By northern blot analysis identical sized transcripts were demonstrated in the prostate, the respiratory (tracheal, bronchial and lung) tissues and the antrum part of the gastric mucosa. Thus, the protein is not primarily associated with male reproductive function. Although probably of no physiological significance, a slight structural similarity to the ovarian inhibin beta-chains was identified in the C-terminal half of the molecule.},
  author       = {Ulvsbäck, M. and Lindstrom, C. and Weiber, Håkan and Abrahamsson, Per-Anders and Lilja, Hans and Lundwall, Åke},
  language     = {eng},
  number       = {3},
  pages        = {5--1310},
  publisher    = {Elsevier},
  series       = {Biochem Biophys Res Commun},
  title        = {Molecular cloning of a small prostate protein, known as beta-microsemenoprotein, PSP94 or beta-inhibin, and demonstration of transcripts in non-genital tissues},
  url          = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2590204},
  volume       = {164},
  year         = {1989},
}