Metabolic and Bariatric Surgery in adolescents – for whom, when, and how?
(2023) In Hormone Research in Paediatrics 96(6). p.609-619- Abstract
- Severe obesity in adolescence profoundly impacts health and social well-being. Lifestyle modifications are seldom successful in maintaining sufficient weight loss to mitigate the risk of complications. Metabolic and bariatric surgery (MBS) is a standard treatment for adult patients and has emerged as an option for adolescent patients. Several high-quality studies of adolescent MBS show substantial and sustained improvements both in weight and cardiometabolic parameters, as well as a safety profile similar to that seen in adult patients. Patients report improvements in health- and weight-related quality of life. Concerns around adolescent MBS can be attributed to a fear of side effects on growth and puberty, risk of nutritional deficiencies... (More)
- Severe obesity in adolescence profoundly impacts health and social well-being. Lifestyle modifications are seldom successful in maintaining sufficient weight loss to mitigate the risk of complications. Metabolic and bariatric surgery (MBS) is a standard treatment for adult patients and has emerged as an option for adolescent patients. Several high-quality studies of adolescent MBS show substantial and sustained improvements both in weight and cardiometabolic parameters, as well as a safety profile similar to that seen in adult patients. Patients report improvements in health- and weight-related quality of life. Concerns around adolescent MBS can be attributed to a fear of side effects on growth and puberty, risk of nutritional deficiencies and osteoporosis, alcohol abuse, psychosocial vulnerability, and the ability to consent in the decision process. Guidelines give somewhat different recommendations, but the most comprehensive guidelines from the American Society for Metabolic and Bariatric Surgery recommend MBS for class III obesity or class II obesity with comorbidity. This mini-review aimed to present published data on MBS in adolescents. We discuss indications for MBS and the optimal timing in the young person’s life, the choice of surgical method, and MBS in relation to the new anti-obesity medications. Based on data primarily from the USA and Sweden, we conclude that MBS is a valuable treatment option for adolescents with severe obesity that appears underutilized against the backdrop of the poor prognosis of severe obesity. We argue for continued research, development of guidelines, multi-professional teamwork, long-term follow-up, and centralization of adolescent MBS. (Less)
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https://lup.lub.lu.se/record/7b4dac7e-4ca3-4e03-9bfe-126190de08e3
- author
- Janson, Annika ; Järvholm, Kajsa LU ; Sjögren, Lovisa ; Dahlgren, Jovanna ; Beamish, Andrew J ; Gronowitz, Eva and Olbers, Torsten
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Hormone Research in Paediatrics
- volume
- 96
- issue
- 6
- pages
- 609 - 619
- publisher
- Karger
- external identifiers
-
- pmid:35263750
- scopus:85179013495
- ISSN
- 1663-2826
- DOI
- 10.1159/000524002
- language
- English
- LU publication?
- yes
- id
- 7b4dac7e-4ca3-4e03-9bfe-126190de08e3
- date added to LUP
- 2022-04-07 13:40:55
- date last changed
- 2024-02-19 04:05:34
@article{7b4dac7e-4ca3-4e03-9bfe-126190de08e3,
abstract = {{Severe obesity in adolescence profoundly impacts health and social well-being. Lifestyle modifications are seldom successful in maintaining sufficient weight loss to mitigate the risk of complications. Metabolic and bariatric surgery (MBS) is a standard treatment for adult patients and has emerged as an option for adolescent patients. Several high-quality studies of adolescent MBS show substantial and sustained improvements both in weight and cardiometabolic parameters, as well as a safety profile similar to that seen in adult patients. Patients report improvements in health- and weight-related quality of life. Concerns around adolescent MBS can be attributed to a fear of side effects on growth and puberty, risk of nutritional deficiencies and osteoporosis, alcohol abuse, psychosocial vulnerability, and the ability to consent in the decision process. Guidelines give somewhat different recommendations, but the most comprehensive guidelines from the American Society for Metabolic and Bariatric Surgery recommend MBS for class III obesity or class II obesity with comorbidity. This mini-review aimed to present published data on MBS in adolescents. We discuss indications for MBS and the optimal timing in the young person’s life, the choice of surgical method, and MBS in relation to the new anti-obesity medications. Based on data primarily from the USA and Sweden, we conclude that MBS is a valuable treatment option for adolescents with severe obesity that appears underutilized against the backdrop of the poor prognosis of severe obesity. We argue for continued research, development of guidelines, multi-professional teamwork, long-term follow-up, and centralization of adolescent MBS.}},
author = {{Janson, Annika and Järvholm, Kajsa and Sjögren, Lovisa and Dahlgren, Jovanna and Beamish, Andrew J and Gronowitz, Eva and Olbers, Torsten}},
issn = {{1663-2826}},
language = {{eng}},
number = {{6}},
pages = {{609--619}},
publisher = {{Karger}},
series = {{Hormone Research in Paediatrics}},
title = {{Metabolic and Bariatric Surgery in adolescents – for whom, when, and how?}},
url = {{http://dx.doi.org/10.1159/000524002}},
doi = {{10.1159/000524002}},
volume = {{96}},
year = {{2023}},
}