Autonomic nerve dysfunction in patients with bolus-specific esophageal dysmotility
(1995) In Dysphagia 10(1). p.44-48- Abstract
- The pathogenetic mechanisms causing esophageal dysmotility is not well understood. We examined 13 patients with solid bolus dysphagia in a radiologic barium study including the swallowing of a 14-mm tablet. In all 13 patients the tablet was caught in the proximal or midesophagus. In 8 patients, the entrapment was associated with symptoms (Group 1) whereas in 5 patients (Group 2), no symptoms were reported. All 13 patients together with a control group of 56 healthy, nondysphagic subjects were tested for autonomic nerve function. Autonomic nerve function tests included registration of electrocardiographic R-R interval variation during deep breathing test (E/I ratio), a test of parasympathetic, vagal, nerve function. The results showed that... (More)
- The pathogenetic mechanisms causing esophageal dysmotility is not well understood. We examined 13 patients with solid bolus dysphagia in a radiologic barium study including the swallowing of a 14-mm tablet. In all 13 patients the tablet was caught in the proximal or midesophagus. In 8 patients, the entrapment was associated with symptoms (Group 1) whereas in 5 patients (Group 2), no symptoms were reported. All 13 patients together with a control group of 56 healthy, nondysphagic subjects were tested for autonomic nerve function. Autonomic nerve function tests included registration of electrocardiographic R-R interval variation during deep breathing test (E/I ratio), a test of parasympathetic, vagal, nerve function. The results showed that the E/I ratio was significantly lower in patients with symptoms of bolus-specific esophageal dysmotility (-2,19 [1.76]) (median [interquartile range]) compared with patients without symptoms (0.05 [2, 87], p = 0.0192) and controls (-0.25 [1.26], p = 0.0009). In conclusion, symptomatic bolus-specific esophageal dysmotility is associated with vagal nerve dysfunction. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1109201
- author
- Ekberg, Olle LU ; Olsson, Rolf LU ; Nilsson, Håkan ; Lilja, Bo and Sundkvist, Göran LU
- organization
- publishing date
- 1995
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Esophagus, Foreign body, Deglutition, Deglutition disorders, Autonomic nerve dysfunction
- in
- Dysphagia
- volume
- 10
- issue
- 1
- pages
- 44 - 48
- publisher
- Springer
- external identifiers
-
- pmid:7859533
- scopus:0028873212
- ISSN
- 1432-0460
- DOI
- 10.1007/BF00261280
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Diabetes Epidemiology and Neuropathy (013241560), Medical Radiology Unit (013241410)
- id
- 7cf45a03-9a4e-469c-baac-a0d25be4fea0 (old id 1109201)
- date added to LUP
- 2016-04-01 11:34:48
- date last changed
- 2021-01-03 05:28:33
@article{7cf45a03-9a4e-469c-baac-a0d25be4fea0,
abstract = {{The pathogenetic mechanisms causing esophageal dysmotility is not well understood. We examined 13 patients with solid bolus dysphagia in a radiologic barium study including the swallowing of a 14-mm tablet. In all 13 patients the tablet was caught in the proximal or midesophagus. In 8 patients, the entrapment was associated with symptoms (Group 1) whereas in 5 patients (Group 2), no symptoms were reported. All 13 patients together with a control group of 56 healthy, nondysphagic subjects were tested for autonomic nerve function. Autonomic nerve function tests included registration of electrocardiographic R-R interval variation during deep breathing test (E/I ratio), a test of parasympathetic, vagal, nerve function. The results showed that the E/I ratio was significantly lower in patients with symptoms of bolus-specific esophageal dysmotility (-2,19 [1.76]) (median [interquartile range]) compared with patients without symptoms (0.05 [2, 87], p = 0.0192) and controls (-0.25 [1.26], p = 0.0009). In conclusion, symptomatic bolus-specific esophageal dysmotility is associated with vagal nerve dysfunction.}},
author = {{Ekberg, Olle and Olsson, Rolf and Nilsson, Håkan and Lilja, Bo and Sundkvist, Göran}},
issn = {{1432-0460}},
keywords = {{Esophagus; Foreign body; Deglutition; Deglutition disorders; Autonomic nerve dysfunction}},
language = {{eng}},
number = {{1}},
pages = {{44--48}},
publisher = {{Springer}},
series = {{Dysphagia}},
title = {{Autonomic nerve dysfunction in patients with bolus-specific esophageal dysmotility}},
url = {{http://dx.doi.org/10.1007/BF00261280}},
doi = {{10.1007/BF00261280}},
volume = {{10}},
year = {{1995}},
}