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IL-17A is Elevated in End-stage COPD and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis.

Roos, Abraham LU ; Sandén, Caroline LU ; Mori, Michiko LU ; Bjermer, Leif LU ; Stampfli, Martin R and Erjefält, Jonas LU (2015) In American Journal of Respiratory and Critical Care Medicine 191(11). p.1232-1241
Abstract
End-stage chronic obstructive pulmonary disease (COPD) is associated with an accumulation of pulmonary lymphoid follicles. Interleukin (IL)-17A is implicated in COPD and pulmonary lymphoid neogenesis in response to microbial stimuli. We hypothesized that IL-17A is increased in peripheral lung tissue during end-stage COPD and also directly contributes to cigarette smoke-induced lymphoid neogenesis.
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
American Journal of Respiratory and Critical Care Medicine
volume
191
issue
11
pages
1232 - 1241
publisher
American Thoracic Society
external identifiers
  • pmid:25844618
  • wos:000356105000010
  • scopus:84930470540
  • pmid:25844618
ISSN
1535-4970
DOI
10.1164/rccm.201410-1861OC
language
English
LU publication?
yes
id
7f6782cd-9842-4708-8767-f6f2a5f24ff7 (old id 5345512)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25844618?dopt=Abstract
date added to LUP
2016-04-01 10:50:59
date last changed
2025-10-14 11:44:10
@article{7f6782cd-9842-4708-8767-f6f2a5f24ff7,
  abstract     = {{End-stage chronic obstructive pulmonary disease (COPD) is associated with an accumulation of pulmonary lymphoid follicles. Interleukin (IL)-17A is implicated in COPD and pulmonary lymphoid neogenesis in response to microbial stimuli. We hypothesized that IL-17A is increased in peripheral lung tissue during end-stage COPD and also directly contributes to cigarette smoke-induced lymphoid neogenesis.}},
  author       = {{Roos, Abraham and Sandén, Caroline and Mori, Michiko and Bjermer, Leif and Stampfli, Martin R and Erjefält, Jonas}},
  issn         = {{1535-4970}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{1232--1241}},
  publisher    = {{American Thoracic Society}},
  series       = {{American Journal of Respiratory and Critical Care Medicine}},
  title        = {{IL-17A is Elevated in End-stage COPD and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis.}},
  url          = {{http://dx.doi.org/10.1164/rccm.201410-1861OC}},
  doi          = {{10.1164/rccm.201410-1861OC}},
  volume       = {{191}},
  year         = {{2015}},
}