Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Data on plasma tumour and metabolism related proteins’ potential in differentiation of HFpEF-PH from PAH and in prognosis of left heart failure patients with pulmonary hypertension

Ahmed, Salaheldin LU orcid ; Ahmed, Abdulla LU orcid and Rådegran, Göran LU (2022) In Data in Brief 40.
Abstract

The data in the current paper constitutes supplementary material to our article entitled “Plasma tumour and metabolism related biomarkers AMBP, LPL and Glyoxalase I differentiate heart failure with preserved ejection fraction with pulmonary hypertension from pulmonary arterial hypertension” Ahmed et al. (2021). The study investigated 69 plasma tumour- and metabolism related proteins in healthy controls (n = 20) and in 115 patients of whom 48 had pulmonary arterial hypertension (PAH; n = 48) and 67 with left heart failure with pulmonary hypertension (LHF-PH) [heart failure with- preserved ejection fraction-PH (HFpEF-PH; n = 31) and reduced ejection fraction-PH (HFrEF-PH; n = 36)]. The haemodynamic data were obtained with right heart... (More)

The data in the current paper constitutes supplementary material to our article entitled “Plasma tumour and metabolism related biomarkers AMBP, LPL and Glyoxalase I differentiate heart failure with preserved ejection fraction with pulmonary hypertension from pulmonary arterial hypertension” Ahmed et al. (2021). The study investigated 69 plasma tumour- and metabolism related proteins in healthy controls (n = 20) and in 115 patients of whom 48 had pulmonary arterial hypertension (PAH; n = 48) and 67 with left heart failure with pulmonary hypertension (LHF-PH) [heart failure with- preserved ejection fraction-PH (HFpEF-PH; n = 31) and reduced ejection fraction-PH (HFrEF-PH; n = 36)]. The haemodynamic data were obtained with right heart catheterization, and clinical data from medical records. The present article describe the plasma levels of tumour- and metabolism related proteins, analyzed with proximity extension assay, along with their uni- and multivariable diagnostic and prognostic potential. High sRAGE levels univariably emerged as a negative prognostic marker in LHF-PH.

(Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cancer, Haemodynamics, HFpEF, PAH, Prognosis, Proteomics, Pulmonary hypertension, Pulmonary hypertension due to left heart disease
in
Data in Brief
volume
40
article number
107747
publisher
Elsevier
external identifiers
  • pmid:35024391
  • scopus:85122007211
ISSN
2352-3409
DOI
10.1016/j.dib.2021.107747
language
English
LU publication?
yes
id
7fd56462-a535-4745-8746-6f5863a18ec5
date added to LUP
2022-03-08 09:32:25
date last changed
2025-01-11 09:12:07
@article{7fd56462-a535-4745-8746-6f5863a18ec5,
  abstract     = {{<p>The data in the current paper constitutes supplementary material to our article entitled “Plasma tumour and metabolism related biomarkers AMBP, LPL and Glyoxalase I differentiate heart failure with preserved ejection fraction with pulmonary hypertension from pulmonary arterial hypertension” Ahmed et al. (2021). The study investigated 69 plasma tumour- and metabolism related proteins in healthy controls (n = 20) and in 115 patients of whom 48 had pulmonary arterial hypertension (PAH; n = 48) and 67 with left heart failure with pulmonary hypertension (LHF-PH) [heart failure with- preserved ejection fraction-PH (HFpEF-PH; n = 31) and reduced ejection fraction-PH (HFrEF-PH; n = 36)]. The haemodynamic data were obtained with right heart catheterization, and clinical data from medical records. The present article describe the plasma levels of tumour- and metabolism related proteins, analyzed with proximity extension assay, along with their uni- and multivariable diagnostic and prognostic potential. High sRAGE levels univariably emerged as a negative prognostic marker in LHF-PH.</p>}},
  author       = {{Ahmed, Salaheldin and Ahmed, Abdulla and Rådegran, Göran}},
  issn         = {{2352-3409}},
  keywords     = {{Cancer; Haemodynamics; HFpEF; PAH; Prognosis; Proteomics; Pulmonary hypertension; Pulmonary hypertension due to left heart disease}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Data in Brief}},
  title        = {{Data on plasma tumour and metabolism related proteins’ potential in differentiation of HFpEF-PH from PAH and in prognosis of left heart failure patients with pulmonary hypertension}},
  url          = {{http://dx.doi.org/10.1016/j.dib.2021.107747}},
  doi          = {{10.1016/j.dib.2021.107747}},
  volume       = {{40}},
  year         = {{2022}},
}