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Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Human C1q Deficiency: The Karolinska Experience.

Olsson, Richard F ; Hagelberg, Stefan ; Schiller, Bodil ; Ringdén, Olle ; Truedsson, Lennart LU and Åhlin, Anders (2015) In Transplantation
Abstract
Human C1q deficiency is associated with systemic lupus erythematosus (SLE) and increased susceptibility to severe bacterial infections. These patients require extensive medical therapy and some develop treatment-resistant disease. Because C1q is produced by monocytes, it has been speculated that allogeneic hematopoietic stem cell transplantation (allo-HSCT) may cure this disorder.
Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Transplantation
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:26516671
  • scopus:84939563568
  • pmid:26516671
  • wos:000377126600032
ISSN
1534-6080
DOI
10.1097/TP.0000000000000975
language
English
LU publication?
yes
id
9a990b3c-88e5-4b03-a400-df3cfd443e08 (old id 8147746)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26516671?dopt=Abstract
date added to LUP
2016-04-04 09:31:53
date last changed
2022-03-08 01:03:23
@article{9a990b3c-88e5-4b03-a400-df3cfd443e08,
  abstract     = {{Human C1q deficiency is associated with systemic lupus erythematosus (SLE) and increased susceptibility to severe bacterial infections. These patients require extensive medical therapy and some develop treatment-resistant disease. Because C1q is produced by monocytes, it has been speculated that allogeneic hematopoietic stem cell transplantation (allo-HSCT) may cure this disorder.}},
  author       = {{Olsson, Richard F and Hagelberg, Stefan and Schiller, Bodil and Ringdén, Olle and Truedsson, Lennart and Åhlin, Anders}},
  issn         = {{1534-6080}},
  language     = {{eng}},
  month        = {{10}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Transplantation}},
  title        = {{Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Human C1q Deficiency: The Karolinska Experience.}},
  url          = {{http://dx.doi.org/10.1097/TP.0000000000000975}},
  doi          = {{10.1097/TP.0000000000000975}},
  year         = {{2015}},
}