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Bradycardia During Targeted Temperature Management: An Early Marker of Lower Mortality and Favorable Neurologic Outcome in Comatose Out-of-Hospital Cardiac Arrest Patients.

Thomsen, Jakob Hartvig; Nielsen, Niklas LU ; Hassager, Christian; Wanscher, Michael; Pehrson, Steen; Køber, Lars; Bro-Jeppesen, John; Søholm, Helle; Winther-Jensen, Matilde and Pellis, Tommaso, et al. (2016) In Critical Care Medicine 44(2). p.308-318
Abstract
Bradycardia is common during targeted temperature management, likely being a physiologic response to lower body temperature, and has recently been associated with favorable outcome following out-of-hospital cardiac arrest in smaller observational studies. The present study sought to confirm this finding in a large multicenter cohort of patients treated with targeted temperature management at 33°C and explore the response to targeted temperature management targeting 36°C.
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type
Contribution to journal
publication status
published
subject
in
Critical Care Medicine
volume
44
issue
2
pages
308 - 318
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:26468897
  • wos:000368503700009
  • scopus:84954330342
ISSN
1530-0293
DOI
10.1097/CCM.0000000000001390
language
English
LU publication?
yes
id
55532dea-4bca-4f5f-8717-41cc5ce5facf (old id 8152195)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26468897?dopt=Abstract
date added to LUP
2015-11-03 13:47:01
date last changed
2017-11-19 03:08:29
@article{55532dea-4bca-4f5f-8717-41cc5ce5facf,
  abstract     = {Bradycardia is common during targeted temperature management, likely being a physiologic response to lower body temperature, and has recently been associated with favorable outcome following out-of-hospital cardiac arrest in smaller observational studies. The present study sought to confirm this finding in a large multicenter cohort of patients treated with targeted temperature management at 33°C and explore the response to targeted temperature management targeting 36°C.},
  author       = {Thomsen, Jakob Hartvig and Nielsen, Niklas and Hassager, Christian and Wanscher, Michael and Pehrson, Steen and Køber, Lars and Bro-Jeppesen, John and Søholm, Helle and Winther-Jensen, Matilde and Pellis, Tommaso and Kuiper, Michael and Erlinge, David and Friberg, Hans and Kjaergaard, Jesper},
  issn         = {1530-0293},
  language     = {eng},
  number       = {2},
  pages        = {308--318},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Critical Care Medicine},
  title        = {Bradycardia During Targeted Temperature Management: An Early Marker of Lower Mortality and Favorable Neurologic Outcome in Comatose Out-of-Hospital Cardiac Arrest Patients.},
  url          = {http://dx.doi.org/10.1097/CCM.0000000000001390},
  volume       = {44},
  year         = {2016},
}