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Mature biofilms of Enterococcus faecalis and Enterococcus faecium are highly resistant to antibiotics.

Holmberg, Anna LU and Rasmussen, Magnus LU (2016) In Diagnostic Microbiology and Infectious Disease 84(1). p.19-21
Abstract
Enterococcus faecalis and Enterococcus faecium are important nosocomial pathogens that form biofilms on implanted materials. We compare the antibiotic sensitivity of bacteria in new (established during 24hours) and mature (established during 120hours) enterococcal biofilms. Mature biofilms contained more bacteria and were much more tolerant to antibiotics, including rifampicin-containing combinations, as judged by determination of minimal biofilm eradication concentrations and by time-kill experiments of bacteria in biofilms formed on beads of bone cement.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diagnostic Microbiology and Infectious Disease
volume
84
issue
1
pages
19 - 21
publisher
Elsevier
external identifiers
  • pmid:26458279
  • wos:000367203800006
  • scopus:84949319522
ISSN
1879-0070
DOI
10.1016/j.diagmicrobio.2015.09.012
language
English
LU publication?
yes
id
ecad1d61-d114-4e19-9649-0f7fc057f8d3 (old id 8152544)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26458279?dopt=Abstract
date added to LUP
2015-11-03 12:02:46
date last changed
2017-11-12 03:11:12
@article{ecad1d61-d114-4e19-9649-0f7fc057f8d3,
  abstract     = {Enterococcus faecalis and Enterococcus faecium are important nosocomial pathogens that form biofilms on implanted materials. We compare the antibiotic sensitivity of bacteria in new (established during 24hours) and mature (established during 120hours) enterococcal biofilms. Mature biofilms contained more bacteria and were much more tolerant to antibiotics, including rifampicin-containing combinations, as judged by determination of minimal biofilm eradication concentrations and by time-kill experiments of bacteria in biofilms formed on beads of bone cement.},
  author       = {Holmberg, Anna and Rasmussen, Magnus},
  issn         = {1879-0070},
  language     = {eng},
  number       = {1},
  pages        = {19--21},
  publisher    = {Elsevier},
  series       = {Diagnostic Microbiology and Infectious Disease},
  title        = {Mature biofilms of Enterococcus faecalis and Enterococcus faecium are highly resistant to antibiotics.},
  url          = {http://dx.doi.org/10.1016/j.diagmicrobio.2015.09.012},
  volume       = {84},
  year         = {2016},
}