Mature biofilms of Enterococcus faecalis and Enterococcus faecium are highly resistant to antibiotics.
(2016) In Diagnostic Microbiology and Infectious Disease 84(1). p.19-21- Abstract
- Enterococcus faecalis and Enterococcus faecium are important nosocomial pathogens that form biofilms on implanted materials. We compare the antibiotic sensitivity of bacteria in new (established during 24hours) and mature (established during 120hours) enterococcal biofilms. Mature biofilms contained more bacteria and were much more tolerant to antibiotics, including rifampicin-containing combinations, as judged by determination of minimal biofilm eradication concentrations and by time-kill experiments of bacteria in biofilms formed on beads of bone cement.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8152544
- author
- Holmberg, Anna LU and Rasmussen, Magnus LU
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Diagnostic Microbiology and Infectious Disease
- volume
- 84
- issue
- 1
- pages
- 19 - 21
- publisher
- Elsevier
- external identifiers
-
- pmid:26458279
- wos:000367203800006
- scopus:84949319522
- pmid:26458279
- ISSN
- 1879-0070
- DOI
- 10.1016/j.diagmicrobio.2015.09.012
- language
- English
- LU publication?
- yes
- id
- ecad1d61-d114-4e19-9649-0f7fc057f8d3 (old id 8152544)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26458279?dopt=Abstract
- date added to LUP
- 2016-04-01 10:42:00
- date last changed
- 2022-04-12 08:48:02
@article{ecad1d61-d114-4e19-9649-0f7fc057f8d3,
abstract = {{Enterococcus faecalis and Enterococcus faecium are important nosocomial pathogens that form biofilms on implanted materials. We compare the antibiotic sensitivity of bacteria in new (established during 24hours) and mature (established during 120hours) enterococcal biofilms. Mature biofilms contained more bacteria and were much more tolerant to antibiotics, including rifampicin-containing combinations, as judged by determination of minimal biofilm eradication concentrations and by time-kill experiments of bacteria in biofilms formed on beads of bone cement.}},
author = {{Holmberg, Anna and Rasmussen, Magnus}},
issn = {{1879-0070}},
language = {{eng}},
number = {{1}},
pages = {{19--21}},
publisher = {{Elsevier}},
series = {{Diagnostic Microbiology and Infectious Disease}},
title = {{Mature biofilms of Enterococcus faecalis and Enterococcus faecium are highly resistant to antibiotics.}},
url = {{http://dx.doi.org/10.1016/j.diagmicrobio.2015.09.012}},
doi = {{10.1016/j.diagmicrobio.2015.09.012}},
volume = {{84}},
year = {{2016}},
}