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S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival.

Bergenfelz, Caroline LU ; Gaber, Alexander LU ; Allaoui, Roni LU ; Mehmeti, Meliha LU ; Jirström, Karin LU ; Leanderson, Tomas LU and Leandersson, Karin LU (2015) In British Journal of Cancer 113(8). p.1234-1243
Abstract
Breast cancer is the most common cancer form among women today. Depending on hormone receptor status, breast cancers are divided into different subtypes with vastly varying prognosis. S100A9 is a calcium-binding protein that is associated with inflammation and expressed not only in myeloid cells but also in some tumours. The role for S100A9 in the malignant cells is not well characterised; however, previous studies have shown that the protein could have important immune-modulating properties.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Cancer
volume
113
issue
8
pages
1234 - 1243
publisher
Nature Publishing Group
external identifiers
  • pmid:26448179
  • wos:000363445400012
  • scopus:84945470244
ISSN
1532-1827
DOI
10.1038/bjc.2015.346
language
English
LU publication?
yes
id
04af3d7a-6ab4-4f40-a742-0217a169a9ec (old id 8158557)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26448179?dopt=Abstract
date added to LUP
2015-11-02 21:03:50
date last changed
2017-11-19 03:00:12
@article{04af3d7a-6ab4-4f40-a742-0217a169a9ec,
  abstract     = {Breast cancer is the most common cancer form among women today. Depending on hormone receptor status, breast cancers are divided into different subtypes with vastly varying prognosis. S100A9 is a calcium-binding protein that is associated with inflammation and expressed not only in myeloid cells but also in some tumours. The role for S100A9 in the malignant cells is not well characterised; however, previous studies have shown that the protein could have important immune-modulating properties.},
  author       = {Bergenfelz, Caroline and Gaber, Alexander and Allaoui, Roni and Mehmeti, Meliha and Jirström, Karin and Leanderson, Tomas and Leandersson, Karin},
  issn         = {1532-1827},
  language     = {eng},
  number       = {8},
  pages        = {1234--1243},
  publisher    = {Nature Publishing Group},
  series       = {British Journal of Cancer},
  title        = {S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival.},
  url          = {http://dx.doi.org/10.1038/bjc.2015.346},
  volume       = {113},
  year         = {2015},
}