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Prediction of hip displacement in children with cerebral palsy : development of the CPUP hip score

Hermanson, Maria LU ; Hägglund, Gunnar LU ; Riad, J; Rodby-Bousquet, E and Wagner, P (2015) In The Bone & Joint Journal 97B(10). p.1441-1444
Abstract

Hip displacement, defined in this study as a migration percentage (MP) of more than 40%, is a common, debilitating complication of cerebral palsy (CP). In this prospective study we analysed the risk of developing hip displacement within five years of the first pelvic radiograph. All children with CP in southern and western Sweden are invited to register in the hip surveillance programme CPUP. Inclusion criteria for the two groups in this study were children from the CPUP database born between 1994 and 2009 with Gross Motor Function Classification System (GMFCS) III to V. Group 1 included children who developed hip displacement, group 2 included children who did not develop hip displacement over a minimum follow-up of five years. A total... (More)

Hip displacement, defined in this study as a migration percentage (MP) of more than 40%, is a common, debilitating complication of cerebral palsy (CP). In this prospective study we analysed the risk of developing hip displacement within five years of the first pelvic radiograph. All children with CP in southern and western Sweden are invited to register in the hip surveillance programme CPUP. Inclusion criteria for the two groups in this study were children from the CPUP database born between 1994 and 2009 with Gross Motor Function Classification System (GMFCS) III to V. Group 1 included children who developed hip displacement, group 2 included children who did not develop hip displacement over a minimum follow-up of five years. A total of 145 children were included with a mean age at their initial pelvic radiograph of 3.5 years (0.6 to 9.7). The odds ratio for hip displacement was calculated for GMFCS-level, age and initial MP and head-shaft angle. A risk score was constructed with these variables using multiple logistic regression analysis. The predictive ability of the risk score was evaluated using the area under the receiver operating characteristics curve (AUC). All variables had a significant effect on the risk of a MP > 40%. The discriminatory accuracy of the CPUP hip score is high (AUC = 0.87), indicating a high ability to differentiate between high- and low-risk individuals for hip displacement. The CPUP hip score may be useful in deciding on further follow-up and treatment in children with CP.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Area Under Curve, Cerebral Palsy, Child, Child, Preschool, Female, Forecasting, Hip Dislocation, Hip Joint, Humans, Infant, Logistic Models, Male, Prospective Studies, Radiography, Journal Article, Research Support, Non-U.S. Gov't
in
The Bone & Joint Journal
volume
97B
issue
10
pages
4 pages
publisher
British Editorial Society of Bone & Joint Surgery
external identifiers
  • pmid:26430023
  • wos:000363600600023
  • scopus:84944325116
ISSN
2049-4408
DOI
10.1302/0301-620X.97B10.35978
language
English
LU publication?
yes
id
6516b7da-a2aa-4716-923d-140d2983f70a (old id 8159077)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26430023?dopt=Abstract
date added to LUP
2015-11-02 16:33:03
date last changed
2017-08-13 03:18:57
@article{6516b7da-a2aa-4716-923d-140d2983f70a,
  abstract     = {<p>Hip displacement, defined in this study as a migration percentage (MP) of more than 40%, is a common, debilitating complication of cerebral palsy (CP). In this prospective study we analysed the risk of developing hip displacement within five years of the first pelvic radiograph. All children with CP in southern and western Sweden are invited to register in the hip surveillance programme CPUP. Inclusion criteria for the two groups in this study were children from the CPUP database born between 1994 and 2009 with Gross Motor Function Classification System (GMFCS) III to V. Group 1 included children who developed hip displacement, group 2 included children who did not develop hip displacement over a minimum follow-up of five years. A total of 145 children were included with a mean age at their initial pelvic radiograph of 3.5 years (0.6 to 9.7). The odds ratio for hip displacement was calculated for GMFCS-level, age and initial MP and head-shaft angle. A risk score was constructed with these variables using multiple logistic regression analysis. The predictive ability of the risk score was evaluated using the area under the receiver operating characteristics curve (AUC). All variables had a significant effect on the risk of a MP &gt; 40%. The discriminatory accuracy of the CPUP hip score is high (AUC = 0.87), indicating a high ability to differentiate between high- and low-risk individuals for hip displacement. The CPUP hip score may be useful in deciding on further follow-up and treatment in children with CP.</p>},
  author       = {Hermanson, Maria and Hägglund, Gunnar and Riad, J and Rodby-Bousquet, E and Wagner, P},
  issn         = {2049-4408},
  keyword      = {Area Under Curve,Cerebral Palsy,Child,Child, Preschool,Female,Forecasting,Hip Dislocation,Hip Joint,Humans,Infant,Logistic Models,Male,Prospective Studies,Radiography,Journal Article,Research Support, Non-U.S. Gov't},
  language     = {eng},
  number       = {10},
  pages        = {1441--1444},
  publisher    = {British Editorial Society of Bone & Joint Surgery},
  series       = {The Bone & Joint Journal},
  title        = {Prediction of hip displacement in children with cerebral palsy : development of the CPUP hip score},
  url          = {http://dx.doi.org/10.1302/0301-620X.97B10.35978},
  volume       = {97B},
  year         = {2015},
}