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Phase I study of cetuximab in combination with 5-fluorouracil, mitomycin C and radiotherapy in patients with locally advanced anal cancer.

Leon, Otilia LU ; Guren, Marianne G; Radu, Calin; Gunnlaugsson, Adalsteinn LU and Johnsson, Anders LU (2015) In European Journal of Cancer 51(18). p.2740-2746
Abstract
5-fluorouracil (5FU) and mitomycin C (MMC)-based chemoradiotherapy (CRT) is standard treatment for anal squamous cell carcinoma. In this phase I study cetuximab was added and the primary aim was to determine the maximum tolerated dose (MTD) of 5FU and MMC in this combination.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Cancer
volume
51
issue
18
pages
2740 - 2746
publisher
IFAC & Elsevier Ltd.
external identifiers
  • pmid:26597443
  • wos:000365624500003
  • scopus:84959496434
ISSN
1879-0852
DOI
10.1016/j.ejca.2015.08.029
language
English
LU publication?
yes
id
db429f8d-1297-4cfa-8935-57def1890502 (old id 8234774)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26597443?dopt=Abstract
date added to LUP
2015-12-02 22:08:50
date last changed
2017-09-24 03:26:17
@article{db429f8d-1297-4cfa-8935-57def1890502,
  abstract     = {5-fluorouracil (5FU) and mitomycin C (MMC)-based chemoradiotherapy (CRT) is standard treatment for anal squamous cell carcinoma. In this phase I study cetuximab was added and the primary aim was to determine the maximum tolerated dose (MTD) of 5FU and MMC in this combination.},
  author       = {Leon, Otilia and Guren, Marianne G and Radu, Calin and Gunnlaugsson, Adalsteinn and Johnsson, Anders},
  issn         = {1879-0852},
  language     = {eng},
  number       = {18},
  pages        = {2740--2746},
  publisher    = {IFAC & Elsevier Ltd.},
  series       = {European Journal of Cancer},
  title        = {Phase I study of cetuximab in combination with 5-fluorouracil, mitomycin C and radiotherapy in patients with locally advanced anal cancer.},
  url          = {http://dx.doi.org/10.1016/j.ejca.2015.08.029},
  volume       = {51},
  year         = {2015},
}