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The GH5 1,4-β-mannanase from Bifidobacterium animalis subsp. lactis Bl-04 possesses a low-affinity mannan-binding module and highlights the diversity of mannanolytic enzymes.

Morrill, Johan LU ; Kulcinskaja, Evelina LU ; Sulewska, Anna Maria; Lahtinen, Sampo; Stålbrand, Henrik LU ; Svensson, Birte and Abou Hachem, Maher (2015) In BMC Biochemistry 16(1).
Abstract
β-Mannans are abundant and diverse plant structural and storage polysaccharides. Certain human gut microbiota members including health-promoting Bifidobacterium spp. catabolize dietary mannans. Little insight is available on the enzymology of mannan deconstruction in the gut ecological niche. Here, we report the biochemical properties of the first family 5 subfamily 8 glycoside hydrolase (GH5_8) mannanase from the probiotic bacterium Bifidobacterium animalis subsp. lactis Bl-04 (BlMan5_8).
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Probiotic bacteria, Surface plasmon resonance, Mannan, Gut microbiota, Carbohydrate-binding module, Bifidobacterium
in
BMC Biochemistry
volume
16
issue
1
publisher
BioMed Central
external identifiers
  • pmid:26558435
  • wos:000364367300001
  • scopus:84947866821
ISSN
1471-2091
DOI
10.1186/s12858-015-0055-4
language
English
LU publication?
yes
id
28e4e473-20c3-4c01-83ee-8c64b62bdee2 (old id 8235983)
date added to LUP
2015-12-16 17:32:26
date last changed
2017-10-22 04:18:37
@article{28e4e473-20c3-4c01-83ee-8c64b62bdee2,
  abstract     = {β-Mannans are abundant and diverse plant structural and storage polysaccharides. Certain human gut microbiota members including health-promoting Bifidobacterium spp. catabolize dietary mannans. Little insight is available on the enzymology of mannan deconstruction in the gut ecological niche. Here, we report the biochemical properties of the first family 5 subfamily 8 glycoside hydrolase (GH5_8) mannanase from the probiotic bacterium Bifidobacterium animalis subsp. lactis Bl-04 (BlMan5_8).},
  articleno    = {26},
  author       = {Morrill, Johan and Kulcinskaja, Evelina and Sulewska, Anna Maria and Lahtinen, Sampo and Stålbrand, Henrik and Svensson, Birte and Abou Hachem, Maher},
  issn         = {1471-2091},
  keyword      = {Probiotic bacteria,Surface plasmon resonance,Mannan,Gut microbiota,Carbohydrate-binding module,Bifidobacterium},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {BMC Biochemistry},
  title        = {The GH5 1,4-β-mannanase from Bifidobacterium animalis subsp. lactis Bl-04 possesses a low-affinity mannan-binding module and highlights the diversity of mannanolytic enzymes.},
  url          = {http://dx.doi.org/10.1186/s12858-015-0055-4},
  volume       = {16},
  year         = {2015},
}