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Molecular analysis of Philadelphia-positive childhood chronic myeloid leukemia.

Fioretos, Thoas LU ; Heim, Sverre LU ; Garwicz, Stanislaw LU ; Ludvigsson, J and Mitelman, Felix LU orcid (1992) In Leukemia 6(7). p.723-725
Abstract
The breakpoints in chromosome 22 were determined in five children with Philadelphia-positive chronic myeloid leukemia. All had rearrangements within the major breakpoint cluster region (M-bcr). Four patients had breakpoints in the 5' region of M-bcr (zones 1-3), whereas one had a rearrangement in the 3' region (zone 4). The patient with the 3' rearrangement was the only one to develop a lymphoid blast crisis; he also had a substantially longer survival (102 months) than the others (11-54 months).
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Leukemia
volume
6
issue
7
pages
723 - 725
publisher
Nature Publishing Group
external identifiers
  • scopus:0026755447
ISSN
1476-5551
language
English
LU publication?
yes
id
82f19ac1-e6c7-43f4-a048-7fbd866b7574 (old id 30092)
date added to LUP
2016-04-01 16:36:31
date last changed
2021-09-19 04:49:07
@article{82f19ac1-e6c7-43f4-a048-7fbd866b7574,
  abstract     = {{The breakpoints in chromosome 22 were determined in five children with Philadelphia-positive chronic myeloid leukemia. All had rearrangements within the major breakpoint cluster region (M-bcr). Four patients had breakpoints in the 5' region of M-bcr (zones 1-3), whereas one had a rearrangement in the 3' region (zone 4). The patient with the 3' rearrangement was the only one to develop a lymphoid blast crisis; he also had a substantially longer survival (102 months) than the others (11-54 months).}},
  author       = {{Fioretos, Thoas and Heim, Sverre and Garwicz, Stanislaw and Ludvigsson, J and Mitelman, Felix}},
  issn         = {{1476-5551}},
  language     = {{eng}},
  number       = {{7}},
  pages        = {{723--725}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Leukemia}},
  title        = {{Molecular analysis of Philadelphia-positive childhood chronic myeloid leukemia.}},
  volume       = {{6}},
  year         = {{1992}},
}