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Long-term follow-up in depressed patients treated with ECT

Johanson, Aki LU ; Gustafson, Lars LU ; Risberg, Jarl LU ; Rosén, Ingmar LU ; Sjöbeck, Martin LU and Silfverskiöld, P (2005) In Journal of ECT 21(4). p.214-220
Abstract
Design: The aim was to study the long-term effects of electroconvulsive therapy (ECT) in depression. 55 patients were followed-up 20-24 years after an ECT series. 13 patients were still alive and 10 agreed to participate in the study. All 55 patients had been investigated with clinical and neuropsychological assessment and with neurophysiological measurements; regional Cerebral Blood Flow (rCBF) and EEG before the first ECT, six months later and after about one year. These investigations were now repeated in the 10 patients.

Results: Before the original ECT series all patients had suffered from severe mood disorder. At the follow-up the 10 patients showed no clear signs of mood disorder or cognitive impairment. There was a... (More)
Design: The aim was to study the long-term effects of electroconvulsive therapy (ECT) in depression. 55 patients were followed-up 20-24 years after an ECT series. 13 patients were still alive and 10 agreed to participate in the study. All 55 patients had been investigated with clinical and neuropsychological assessment and with neurophysiological measurements; regional Cerebral Blood Flow (rCBF) and EEG before the first ECT, six months later and after about one year. These investigations were now repeated in the 10 patients.

Results: Before the original ECT series all patients had suffered from severe mood disorder. At the follow-up the 10 patients showed no clear signs of mood disorder or cognitive impairment. There was a slightly subnormal performance in working memory and in verbal as well as visual episodic memory on all three occasions after the ECT series. The rCBF measurement showed a significant average CBF decrease from the first to the last measurement. There was, moreover, a significant rCBF decrease in frontal areas at the last measurement compared to the three previous assessments.

Conclusion: All ten patients followed-up 20 – 24 years after an ECT series were mentally healthy and thus besides a moderate visual memory dysfunction no severe side effects were observed with clinical and neuroimaging techniques. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of ECT
volume
21
issue
4
pages
214 - 220
publisher
Lippincott Williams & Wilkins
ISSN
1533-4112
language
English
LU publication?
yes
id
b13f7e24-945f-4023-9aac-67839dd94bf0 (old id 833588)
date added to LUP
2008-01-30 12:18:16
date last changed
2016-04-15 20:33:39
@article{b13f7e24-945f-4023-9aac-67839dd94bf0,
  abstract     = {Design: The aim was to study the long-term effects of electroconvulsive therapy (ECT) in depression. 55 patients were followed-up 20-24 years after an ECT series. 13 patients were still alive and 10 agreed to participate in the study. All 55 patients had been investigated with clinical and neuropsychological assessment and with neurophysiological measurements; regional Cerebral Blood Flow (rCBF) and EEG before the first ECT, six months later and after about one year. These investigations were now repeated in the 10 patients. <br/><br>
Results: Before the original ECT series all patients had suffered from severe mood disorder. At the follow-up the 10 patients showed no clear signs of mood disorder or cognitive impairment. There was a slightly subnormal performance in working memory and in verbal as well as visual episodic memory on all three occasions after the ECT series. The rCBF measurement showed a significant average CBF decrease from the first to the last measurement. There was, moreover, a significant rCBF decrease in frontal areas at the last measurement compared to the three previous assessments. <br/><br>
Conclusion: All ten patients followed-up 20 – 24 years after an ECT series were mentally healthy and thus besides a moderate visual memory dysfunction no severe side effects were observed with clinical and neuroimaging techniques.},
  author       = {Johanson, Aki and Gustafson, Lars and Risberg, Jarl and Rosén, Ingmar and Sjöbeck, Martin and Silfverskiöld, P},
  issn         = {1533-4112},
  language     = {eng},
  number       = {4},
  pages        = {214--220},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Journal of ECT},
  title        = {Long-term follow-up in depressed patients treated with ECT},
  volume       = {21},
  year         = {2005},
}