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Precision nutrition for cardiometabolic diseases

Guasch-Ferré, Marta ; Wittenbecher, Clemens ; Palmnäs, Marie ; Ben-Yacov, Orly ; Blaak, Ellen E. ; Dahm, Christina C. ; Fall, Tove ; Heitmann, Berit L. ; Licht, Tine R. and Löf, Marie , et al. (2025) In Nature Medicine 31(5). p.1444-1453
Abstract

Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and between-person variability in responses to diet. These studies illustrate the promise of precision nutrition to complement the traditional ‘one size fits all’ dietary guidelines, which, while considering broad life-stage and disease-specific nutritional requirements, often lack the granularity to account fully for individual variations in... (More)

Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and between-person variability in responses to diet. These studies illustrate the promise of precision nutrition to complement the traditional ‘one size fits all’ dietary guidelines, which, while considering broad life-stage and disease-specific nutritional requirements, often lack the granularity to account fully for individual variations in nutritional needs and dietary responses. Despite these developments, however, considerable challenges remain before precision nutrition can be implemented on a broader scale. This Review examines the current state of precision nutrition research, with a focus on its application to reducing the incidence and burden of cardiometabolic diseases. We critically examine the evidence base, explore the potential benefits and discuss the challenges and opportunities ahead.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nature Medicine
volume
31
issue
5
pages
10 pages
publisher
Nature Publishing Group
external identifiers
  • scopus:105003943828
  • pmid:40307513
ISSN
1078-8956
DOI
10.1038/s41591-025-03669-9
language
English
LU publication?
yes
additional info
Publisher Copyright: © Springer Nature America, Inc. 2025.
id
83e4cddc-5b6d-4ddb-beb9-2948a0ef6b21
date added to LUP
2025-08-11 15:35:36
date last changed
2025-09-08 17:37:59
@article{83e4cddc-5b6d-4ddb-beb9-2948a0ef6b21,
  abstract     = {{<p>Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and between-person variability in responses to diet. These studies illustrate the promise of precision nutrition to complement the traditional ‘one size fits all’ dietary guidelines, which, while considering broad life-stage and disease-specific nutritional requirements, often lack the granularity to account fully for individual variations in nutritional needs and dietary responses. Despite these developments, however, considerable challenges remain before precision nutrition can be implemented on a broader scale. This Review examines the current state of precision nutrition research, with a focus on its application to reducing the incidence and burden of cardiometabolic diseases. We critically examine the evidence base, explore the potential benefits and discuss the challenges and opportunities ahead.</p>}},
  author       = {{Guasch-Ferré, Marta and Wittenbecher, Clemens and Palmnäs, Marie and Ben-Yacov, Orly and Blaak, Ellen E. and Dahm, Christina C. and Fall, Tove and Heitmann, Berit L. and Licht, Tine R. and Löf, Marie and Loos, Ruth and Patel, Chirag J. and Quarta, Carmelo and Redman, Leanne M. and Segal, Eran and Segata, Nicola and Snyder, Michael and Sun, Qi and Tobias, Deirdre K. and Hu, Frank B. and Franks, Paul W. and Landberg, Rikard and Sargent, Jennifer L. and Merino, Jordi}},
  issn         = {{1078-8956}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{1444--1453}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Nature Medicine}},
  title        = {{Precision nutrition for cardiometabolic diseases}},
  url          = {{http://dx.doi.org/10.1038/s41591-025-03669-9}},
  doi          = {{10.1038/s41591-025-03669-9}},
  volume       = {{31}},
  year         = {{2025}},
}